About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:76228 Sato M, et al., Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells. Mech Dev. 2002 Apr;113(1):91-4
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3783517
Gene symbol: Dppa3
Gene name: developmental pluripotency-associated 3
Antibody: anti-PGC7
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2Aa: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: primary oocyte Present 2Aa Expression is present in oocytes but no other ovarian cell type.
TS28: ovary Present Regionally restricted 2Aa Expression is present in oocytes but no other ovarian cell type.

Specimen 2Ab: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: testis Absent 2Ab There is no expression in the male gonad.

Specimen 2Ba: postnatal adult (more )
Structure Level Pattern Image Note
TS28: primary oocyte Present Regionally restricted 2Ba Expression is present primarily in the cytoplasm of primary oocytes and oocytes within mono-laminar follicles.

Specimen 2Bb: postnatal adult (more )
Structure Level Pattern Image Note
TS28: primary oocyte Present 2Bb Expression is present in both the nucleus and cytoplasm of oocytes in bi-laminar follicles.

Specimen 2Bc: postnatal adult (more )
Structure Level Pattern Image Note
TS28: primary oocyte Present 2Bc Expression is present in both the nucleus and cytoplasm of oocytes in Graffian follicles.

Specimen 3Aa: postnatal (more )
Structure Level Pattern Image Note
TS28: secondary oocyte Present Diffuse 3Aa Expression is diffusely distributed throughout the unfertilized egg.

Specimen 3Ab: embryonic day 0.5 (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Non-Uniform 3Ab Expression is localized to the two pronuclei; its localization in the cytoplasm is significantly decreased.
TS1: polar body Present 3Ab

Specimen 3Ac: embryonic day 1.0 (more )
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present Diffuse 3Ac Expression is localized diffusely both in the nucleus and cytoplasm.

Specimen 3Ad: embryonic day 2.0 (more )
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present Diffuse 3Ad Expression is localized diffusely both in the nucleus and cytoplasm.

Specimen 3Ae: embryonic day 2.5 (more )
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Diffuse 3Ae Expression is localized diffusely both in the nucleus and cytoplasm.

Specimen 3Af: embryonic day 3.0 (more )
Structure Level Pattern Image Note
TS4: compacted morula Present Diffuse 3Af Expression is localized diffusely both in the nucleus and cytoplasm.

Specimen 3Ag: embryonic day 3.5 (more )
Note: This is a blastocyst.
Structure Level Pattern Image Note
TS5: inner cell mass Present Non-Uniform 3Ag Expression is mainly localized in the nucleus.
TS5: trophectoderm Present Non-Uniform 3Ag Expression is mainly localized in the nucleus.

Specimen 3Ba: embryonic day 1.0 (more )
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present Diffuse 3Ba , 3Bg Expression is localized diffusely both in the nucleus and cytoplasm.

Specimen 3Bb: embryonic day 2.5 (more )
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Diffuse 3Bb , 3Bh Expression is localized diffusely both in the nucleus and cytoplasm.

Specimen 3Bc: embryonic day 3.5 (more )
Note: This is a blastocyst.
Structure Level Pattern Image Note
TS5: inner cell mass Present Non-Uniform 3Bi , 3Bc Expression is mainly localized in the nucleus.
TS5: trophectoderm Present Non-Uniform 3Bi , 3Bc Expression is mainly localized in the nucleus.

Specimen Not shown: embryonic day 5.5 (more )
Structure Level Pattern Image Note
TS7: epiblast Absent

Specimen 4Aa: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: primordial germ cell Present 4Aa Expression is present in the cells at the base of and within the allantois.

Specimen 4Ab: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: primordial germ cell of hindgut Present 4Ab Expression is present in cells that have moved into the hindgut wall.

Specimen 4Ac: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: primordial germ cell of dorsal mesentery Present 4Ac Expression is present in cells that have migrated along the dorsal mesentery toward the developing genital ridge.

Specimen 4Ba: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: germ cell of ovary Present 4Ba

Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: germ cell of ovary Present Regionally restricted The majority of germ cells have lost expression; only some cell clusters show any staining.

Specimen 4Bb: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: ovary Absent 4Bb There is no expression in the female gonad.
TS24: germ cell of ovary Absent 4Bb

Specimen 4Bc: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: oocyte Weak 4Bc

Specimen 4Ca: embryonic day 12.5-13.5 (more )
Structure Level Pattern Image Note
TS21: germ cell of testis Present 4Ca

Specimen 4Cb: embryonic day 15.5-16.5 (more )
Structure Level Pattern Image Note
TS24: germ cell of testis Present 4Cb

Specimen 4Cc: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: testis Absent 4Cc


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory