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Gene Expression Data
Assay Details
Assay
Reference: J:98502 Strumpf D, et al., Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development. 2005 May;132(9):2093-102
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3777394
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-uvomorulin/E-Cadherin (DECMA-1), rat
Detection system: Secondary antibody
Results
Specimen 3C: embryonic day 3.25; Cdx2tm1Fbe/Cdx2+ (more )
Note: This is an early blastocyst. Double labeled: green - Cdh1; red - Tjp1 (assay MGI:3777396).
Structure Level Pattern Image Note
TS4: blastocyst Present Non-Uniform 3C This protein localizes to the adherens junction.

Specimen 3D: embryonic day 3.25; Cdx2tm1Fbe/Cdx2tm1Fbe (more )
Note: This is an early blastocyst. Double labeled: green - Cdh1; red - Tjp1 (assay MGI:3777396).
Structure Level Pattern Image Note
TS4: blastocyst Present Non-Uniform 3D This protein localizes to the adherens junction. Its localization appears grossly normal in mutants compared to non-mutant genotypes.

Specimen 3G: embryonic day 4.0; Cdx2tm1Fbe/Cdx2+ (more )
Note: This is a late blastocyst.
Structure Level Pattern Image Note
TS5: trophectoderm Present Regionally restricted 3G This protein localizes to the adherens junction.

Specimen 3H: embryonic day 4.0; Cdx2tm1Fbe/Cdx2tm1Fbe (more )
Note: This is a late blastocyst.
Structure Level Pattern Image Note
TS5: trophectoderm Present Regionally restricted 3H This protein localizes to the adherens junction. In mutants the staining appears to be mislocalized basally, suggesting the polarity is not maintained in the mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory