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Gene Expression Data
Assay Details
Assay
Reference: J:127437 Metzger M, et al., Gene expression of the repulsive guidance molecules during development of the mouse intestine. Dev Dyn. 2005 Sep;234(1):169-75
Assay type: RNA in situ
MGI Accession ID: MGI:3772476
Gene symbol: Rgma
Gene name: repulsive guidance molecule family member A
Probe: Rgma probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: A tyramine biotin based amplification step was used.
Results
Specimen 2A,C: embryonic day 14.0 (more )
Note: C is a higher magnifications of the boxed area in A.
Structure Level Pattern Image Note
TS22: central nervous system Strong 2A
TS22: gut Strong 2A , 2C Expression is in the wall of the digestive tract.
Specimen Not shown P newborn: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: enteric nervous system Present
Specimen Not shown P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: intestine Present Regionally restricted Expression is in intestinal epithelial cells.
Specimen 3E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: myenteric nerve plexus Present 3E
TS28: submucous nerve plexus Present 3E
TS28: intestine epithelium Present Regionally restricted 3E
Specimen 3F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: enteric nervous system Present 3F Shown is the colon between the inner circular and the outer longitudinal muscle layers and in ganglia cells of the submucosa.
TS28: intestine epithelium Present 3F
Specimen 4A: postnatal adult (more )
Note: Double labeled: red - Rgma; brown - neurofilament.
Structure Level Pattern Image Note
TS28: enteric nervous system Present Regionally restricted 4A Expression is in enteric neurons of the gut.
Specimen 4B: postnatal adult (more )
Note: Double labeled: red - Rgma; brown - neurofilament.
Structure Level Pattern Image Note
TS28: enteric nervous system Present Regionally restricted 4B Expression is in enteric neurons of the gut.
Specimen 4C: postnatal adult (more )
Note: Double labeled: red - Rgma; brown - Lyz1 (assay MGI:6469948) and Lyz2 (assay MGI:3772480).
Structure Level Pattern Image Note
TS28: small intestine epithelium Present Regionally restricted 4C Expression is in epithelial cells in the crypt base.
TS28: small intestine Present Regionally restricted 4C Expression is in Paneth cells.
Specimen 4D: postnatal adult (more )
Note: Double labeled: red - Rgma; brown - Lyz1 (assay MGI:6469948) and Lyz2 (assay MGI:3772480).
Structure Level Pattern Image Note
TS28: small intestine epithelium Present Regionally restricted 4D Expression is in epithelial cells in the crypt base.
TS28: small intestine Present Regionally restricted 4D Expression is in Paneth cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory