About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:1921 Timsit SG, et al., DM-20 mRNA is expressed during the embryonic development of the nervous system of the mouse. J Neurochem. 1992 Mar;58(3):1172-5
Assay type: RNA in situ
MGI Accession ID: MGI:3770028
Gene symbol: Plp1
Gene name: proteolipid protein (myelin) 1
Probe: pBS-DM-20
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 2a: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: central nervous system Present Regionally restricted 2a Expression in CNS is bilateral and symmetrical in ventral part of neural tube, limited to the diencephalic region.
TS16: diencephalon Present 2a
TS16: trigeminal ganglion Strong 2a
TS16: spinal ganglion Strong Regionally restricted 2a Strong expression in caudal spinal ganglia.
TS16: peripheral nervous system Strong Regionally restricted 2a Expression in the sympathetic ganglion chain.

Specimen not shown: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: diencephalon Present Uniform Expression in diencephalic region is evenly distributed throughout the cellular layers of the neural tube.

Specimen 2b: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: diencephalon Present Regionally restricted 2b Close to median line, expression in diencephalic region is hardly seen.
TS16: spinal ganglion Strong Regionally restricted 2b Strong expression in caudal spinal ganglia.
TS16: glossopharyngeal-vagus ganglion complex Present 2b Authors report expression in the vasal/glossopharyngeal ganglion.

Specimen not shown: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: diencephalon Present Regionally restricted Expression was seen only on a few adjacent sections at a certain distance on either side of the median line, suggesting restriction to the basal plate.

Specimen 3: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: diencephalon Present Regionally restricted 3 At a distance from the median line, clear expression in the diencephalic basal plate.
TS16: trigeminal ganglion Present 3

Specimen 4: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum Present Regionally restricted 4 Expression in the cerebellum mostly restricted to the white matter.
TS27: cerebellum white matter Present 4 Expression in the cerebellum mostly restricted to the white matter.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/28/2026
MGI 6.24
The Jackson Laboratory