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Gene Expression Data
Assay Details
Assay
Reference: J:101025 Yaylaoglu MB, et al., Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform. Dev Dyn. 2005 Oct;234(2):371-86
Assay type: RNA in situ
MGI Accession ID: MGI:3767160
Gene symbol: Fgf18
Gene name: fibroblast growth factor 18
Probe: FG55 probe 14
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Cryosections of fresh frozen material were fixed in 4% paraformaldehyde for 15-30 min. before further processing. A dual signal amplification strategy, termed catalyzed reporter deposition (CARD), was used for detection.
Results
Specimen FG55: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex marginal layer Present FG55
TS22: forebrain Present Regionally restricted FG55 Expression is present in the neuroepithelium of the lamina terminalis region.
TS22: diencephalon Present Regionally restricted FG55 Expression is present in the midline neuroepithelium lining the floor of the third ventricle.
TS22: hindbrain Present Regionally restricted FG55 Expression is present at the midbrain/hindbran boundary.
TS22: midbrain Present Regionally restricted FG55 Expression is present at the midbrain/hindbran boundary.
TS22: medulla oblongata Present Regionally restricted FG55 Expression is present in certain nuclei.
TS22: pons Present Regionally restricted FG55 Expression is present in certain nuclei.
TS22: midbrain tegmentum Very strong Regionally restricted FG55 Expression is present in a cluster of cells.
TS22: optic chiasma Present FG55
TS22: spinal cord Present Regionally restricted FG55 Expression is present in the ventral region.
TS22: cranial ganglion Present FG55
TS22: dorsal root ganglion Present FG55
TS22: olfactory cortex Present Regionally restricted FG55 Expression is present in a subpopulation of neurons in the olfactory neuroepithelium.
TS22: skeleton Strong Regionally restricted FG55 There is prominent expression in the joints.
TS22: appendicular skeleton Present Regionally restricted FG55 Expression is present in the perichondrium of long bones of limbs.
TS22: axial skeleton Present FG55
TS22: intervertebral disc Present FG55
TS22: rib cartilage condensation Present FG55
TS22: sternum Present FG55
TS22: chondrocranium Present Regionally restricted FG55 Expression is present in the osteogenic mesenchyme around the brain.
TS22: lower jaw Present FG55
TS22: upper jaw Present FG55
TS22: trunk mesenchyme Present Regionally restricted FG55 Expression is present in tissue surrounding the kidney and adrenal.
TS22: lung mesenchyme Present Regionally restricted FG55 Expression is present in lung mesenchyme surrounding the airway epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory