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Gene Expression Data
Assay Details
Assay
Reference: J:1461 Simeone A, et al., Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 1992 Jul;11(7):2541-50
Assay type: RNA in situ
MGI Accession ID: MGI:3766945
Gene symbol: Emx1
Gene name: empty spiracles homeobox 1
Probe: Emx1 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 2a Expression in presumptive cortex from posterior to anterior boundary
TS20: telencephalon Present Regionally restricted 2a No expression in non-cortical basal telencephalic regions.

Specimen 2b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 2b Expression in presumptive cortex from posterior to anterior boundary.
TS20: telencephalon Present Regionally restricted 2b No expression in non-cortical basal telencephalic regions.

Specimen 2c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 2c Expression in presumptive cortex from posterior to anterior boundary.
TS20: telencephalon Present Regionally restricted 2c No expression in non-cortical basal telencephalic regions.

Specimen 2d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 2d Expression in presumptive cortex from posterior to anterior boundary.
TS20: telencephalon Present Regionally restricted 2d Expression in the olfactory bulb. No expression in non-cortical basal telencephalic regions.

Specimen 2e: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 2e Expression in presumptive cortex from posterior to anterior boundary.
TS20: telencephalon Present Regionally restricted 2e No expression in non-cortical basal telencephalic regions.

Specimen 2k: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Non-Uniform 2k

Specimen 2n: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present 2n Expression is similar to that seen at E12.5
TS21: telencephalon Present Regionally restricted 2n Authors report a single spot of non-cortical expression, probably corresponding to a periventricular complex at the posterior boundary of the diencephalon.

Specimen 2o: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present 2o Expression is similar to that seen at E12.5
TS21: telencephalon Present Regionally restricted 2o Authors report a single spot of non-cortical expression, probably corresponding to a periventricular complex at the posterior boundary of the diencephalon.

Specimen 3a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3a
TS20: telencephalon Present Regionally restricted 3a Non-cortical expression domain in presumptive periventricular nuclei

Specimen 3b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3b

Specimen 3c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3c

Specimen 3d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3d

Specimen 3m: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3m
TS20: telencephalon Present Regionally restricted 3m Restricted expression in dorsal regions of lateral ventricles including hippocampal and parahippocampal areas

Specimen 3n: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3n
TS20: telencephalon Present Regionally restricted 3n Restricted expression in dorsal regions of lateral ventricles including hippocampal and parahippocampal areas

Specimen 3o: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3o
TS20: telencephalon Present Regionally restricted 3o Authors report non-cortical expression.

Specimen 4a: embryonic day 9.5 (more )
Note: 22-23 somites.
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted 4a
TS15: branchial arch ectoderm Present 4a

Specimen 4b: embryonic day 9.75 (more )
Note: 27 somites.
Structure Level Pattern Image Note
TS16: future brain Present Regionally restricted 4b Antero-posterior delimitation of expression domain is more evident, with a posterior boundary probably coinciding with that between presumptive diencephalon and telencephalon.
TS16: branchial arch ectoderm Absent 4b

Specimen not shown: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: embryo Present Regionally restricted Authors report expression patterns identical to that seen in E13.5 embryos.

Specimen 5a: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: head Present Regionally restricted 5a
TS25: lens Present 5a
TS25: main olfactory bulb Present 5a

Specimen 5b: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: head Present Regionally restricted 5b

Specimen 5c: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: head Present Regionally restricted 5c
TS25: cerebral cortex Present 5c Reduced cortical expression.
TS25: hippocampus Present Regionally restricted 5c Expression in hippocampal germinal layer.

Specimen 5d: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: head Present Regionally restricted 5d
TS25: cerebral cortex Present Regionally restricted 5d Reduced cortical expression. Expression in primordium of the amigdaloid cortical complex.
TS25: hippocampus Present Regionally restricted 5d Expression in hippocampal germinal layer.

Specimen 5e: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: head Present Regionally restricted 5e
TS25: cerebral cortex Present 5e Reduced cortical expression.
TS25: hippocampus Present Regionally restricted 5e Expression in hippocampal germinal layer.

Specimen 5k: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: head Present Regionally restricted 5k
TS25: cerebral cortex Present Regionally restricted 5k Reduced cortical expression. Expression in primordium of the amigdaloid cortical complex.
TS25: hippocampus Present Regionally restricted 5k Expression in hippocampal germinal layer.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory