Gene Expression Data
Assay Details
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Assay
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Reference:
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J:47920
Dattani MT, et al., Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse. Nat Genet. 1998 Jun;19(2):125-33
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3711941
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Gene symbol:
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Fgf8
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Gene name:
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fibroblast growth factor 8
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Results
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Specimen
3e:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Hesx1tm1Icar/Hesx1tm1Icar
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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This embryo contains 14 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: prosencephalon |
Present |
Regionally restricted |
3e
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Expression is present in the commissural plate, but its domain is greatly reduced in the mutant compared to what is seen in wild type.
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| TS14: future hindbrain |
Present |
Regionally restricted |
3e
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Expression is present in the midbrain-hindbrain boundary. Its domain is similar in mutants and wild type.
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| TS14: future midbrain |
Present |
Regionally restricted |
3e
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Expression is present in the midbrain-hindbrain boundary. Its domain is similar in mutants and wild type.
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Specimen
3f:
embryonic day 8.5
(more  )
Note: This embryo contains 14 somites.
Specimen
3f:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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This embryo contains 14 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: prosencephalon |
Present |
Regionally restricted |
3f
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Expression is present in the commissural plate.
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| TS14: future hindbrain |
Present |
Regionally restricted |
3f
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Expression is present in the midbrain-hindbrain boundary.
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| TS14: future midbrain |
Present |
Regionally restricted |
3f
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Expression is present in the midbrain-hindbrain boundary.
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Specimen
3g:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Hesx1tm1Icar/Hesx1tm1Icar
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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This embryo contains 30 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: future forebrain |
Present |
Regionally restricted |
3g
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Expression is present in the commissural plate, but its domain is greatly reduced in the mutant compared to what is seen in wild type.
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| TS16: nasal pit |
Present |
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3g
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Expression is present in the olfactory placode, but its domain is greatly reduced in the mutant compared to what is seen in wild type.
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Specimen
3h:
embryonic day 10.0
(more )
Note: This embryo contains 30 somites.
Specimen
3h:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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This embryo contains 30 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: future forebrain |
Present |
Regionally restricted |
3h
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Expression is present in the commissural plate.
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| TS16: nasal pit |
Present |
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3h
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Expression is present in the olfactory placodes.
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Analysis Tools