Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:44118
Peyron F, et al., In situ expression of PLP/DM-20, MBP, and CNP during embryonic and postnatal development of the jimpy mutant and of transgenic mice overexpressing PLP. J Neurosci Res. 1997 Oct 15;50(2):190-201
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:3711640
|
|
Gene symbol:
|
Plp1
|
|
Gene name:
|
proteolipid protein (myelin) 1
|
|
Probe:
|
pBS-DM-20
|
|
Probe preparation:
|
Antisense labelled with S35 RNA
|
|
Visualized with:
|
Autoradiography
|
|
|
Results
|
Specimen
1A:
embryonic day 12.5
(more  )
Specimen
1A:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
1C:
embryonic day 14.5
(more )
Specimen
1C:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
1E:
embryonic day 14.5
(more )
Specimen
1E:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
2A:
embryonic day 14.5
(more )
Specimen
2A:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: olfactory lobe |
Present |
Regionally restricted |
2A
|
Expression was detected in the olfactory bulb.
|
| TS22: diencephalon |
Present |
Regionally restricted |
2A
|
Expression was detected in the laterobasal plate of the diencephalon.
|
Specimen
2C:
embryonic day 14.5
(more )
Specimen
2C:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
2E:
embryonic day 14.5
(more )
Specimen
2E:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
3A:
embryonic day 9.5
(more )
Specimen
3A:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
3B:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Mutant Allele(s):
|
Plp1jp/Plp1jp
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
3C:
embryonic day 12.5
(more )
Specimen
3C:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: diencephalon |
Present |
Regionally restricted |
3C
|
Expression was detected in the laterobasal plate of the diencephalon.
|
| TS20: hypothalamus |
Present |
Regionally restricted |
3C
|
Expression was detected in ventral hypothalamus.
|
Specimen
3D:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Mutant Allele(s):
|
Plp1jp/Plp1jp
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: diencephalon |
Present |
Regionally restricted |
3D
|
Expression was detected in the laterobasal plate of the diencephalon as in wild type.
|
| TS20: hypothalamus |
Present |
Regionally restricted |
3D
|
Expression was detected in ventral hypothalamus.
|
Specimen
4A:
embryonic day 14.5
(more )
Specimen
4A:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
4B:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Mutant Allele(s):
|
Plp1jp/Plp1jp
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: embryo |
Present |
|
4B
|
Expression was similar in mutant and control.
|
Specimen
4C:
embryonic day 17.5
(more )
Specimen
4C:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Age:
|
embryonic day 17.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
4D:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Mutant Allele(s):
|
Plp1jp/Plp1jp
|
|
Age:
|
embryonic day 17.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS25: embryo |
Present |
|
4D
|
Expression was similar in mutant and control.
|
Specimen
5A:
postnatal day 1
(more )
Specimen
5A:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
5B:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Mutant Allele(s):
|
Plp1jp/Plp1jp
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: mouse |
Present |
|
5B
|
The pattern and intensity of expression was equivalent to control.
|
| TS27: cerebral hemisphere white matter |
Present |
|
5B
|
Expression was detected in the subcortical white matter as in control.
|
Specimen
5C:
postnatal day 5
(more )
Specimen
5C:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Age:
|
postnatal day 5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
5D:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Mutant Allele(s):
|
Plp1jp/Plp1jp
|
|
Age:
|
postnatal day 5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mouse |
Present |
|
5D
|
The pattern and intensity of expression was equivalent to control.
|
| TS28: cerebral hemisphere white matter |
Present |
Regionally restricted |
5D
|
Expression was detected in the subcortical white matter as in control.
|
Specimen
6A:
postnatal day 15
(more )
Specimen
6A:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: brain |
Present |
|
6A
|
|
Specimen
6B:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Mutant Allele(s):
|
Plp1jp/Plp1jp
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: brain |
Present |
|
6B
|
Distribution of expression signal was the same as in control, but the intensity was decreased in the mutant.
|
Specimen
7A:
postnatal day 22
(more )
Specimen
7A:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Age:
|
postnatal day 22
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: brain |
Present |
|
7A
|
|
Specimen
7B:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Mutant Allele(s):
|
Plp1jp/Plp1jp
|
|
Age:
|
postnatal day 22
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: brain |
Present |
|
7B
|
Distribution of expression signal was the same as in control, but the intensity was decreased in the mutant.
|
Specimen
8A:
postnatal day 30
(more )
Specimen
8A:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Age:
|
postnatal day 30
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: brain |
Present |
|
8A
|
|
Specimen
8B:
(close )
|
Genetic Background:
|
involves: C57BL/6 * CBA
|
|
Mutant Allele(s):
|
Plp1jp/Plp1jp
|
|
Age:
|
postnatal day 30
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: brain |
Present |
|
8B
|
Distribution of expression signal was the same as in control, but the intensity was decreased in the mutant.
|
Specimen
9A:
embryonic day 12.5
(more )
Specimen
9A:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
9C:
embryonic day 14.5
(more )
Specimen
9C:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Analysis Tools