Gene Expression Data
Assay Details
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Assay
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Reference:
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J:55691
Trommsdorff M, et al., Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell. 1999 Jun 11;97(6):689-701
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3707555
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Gene symbol:
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Map2
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Gene name:
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microtubule-associated protein 2
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Antibody:
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Anti-MAP2
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
4i:
postnatal day 20
(more  )
Specimen
4i:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 20
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Present |
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4i
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Expression was detected in neurons and a dense network of radial projections.
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Specimen
4j:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Vldlrtm1Her/Vldlrtm1Her
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Age:
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postnatal day 20
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Present |
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4j
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Expression was detected in neurons and a dense network of radial projections as in wild type.
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Specimen
4k:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Lrp8tm1Her/Lrp8tm1Her
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Age:
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postnatal day 20
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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|
Embedding:
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Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Present |
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4k
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Expression was detected in neurons and a dense network of radial projections as in wild type.
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Specimen
4l:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * 129S7/SvEvBrd
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Mutant Allele(s):
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Lrp8tm1Her/Lrp8tm1Her
Vldlrtm1Her/Vldlrtm1Her
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Age:
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postnatal day 20
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Present |
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4l
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Phenotypic defects in the dense network of radial projections emanating from hippocampal neurons were noted.
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Specimen
4m:
postnatal day 20
(more )
Specimen
4m:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 20
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
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4m
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Neuronal processes were arranged in a radial pattern spanning layers 2-6.
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Specimen
4n:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Vldlrtm1Her/Vldlrtm1Her
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Age:
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postnatal day 20
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
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4n
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Neuronal processes were arranged in a radial pattern spanning layers 2-6, but extended to layer 1 and was more diffuse than wild type.
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Specimen
4o:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Lrp8tm1Her/Lrp8tm1Her
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Age:
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postnatal day 20
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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|
Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
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4o
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The radial pattern of neuronal processes was poorly developed.
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Specimen
4p:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * 129S7/SvEvBrd
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Mutant Allele(s):
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Lrp8tm1Her/Lrp8tm1Her
Vldlrtm1Her/Vldlrtm1Her
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Age:
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postnatal day 20
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Absent |
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4p
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The radial pattern of neuronal processes was completely absent in the double mutant.
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Analysis Tools
