Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:119269
Caqueret A, et al., Laminar organization of the early developing anterior hypothalamus. Dev Biol. 2006 Oct 1;298(1):95-106
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:3703599
|
Gene symbol:
|
Sim1
|
Gene name:
|
single-minded family bHLH transcription factor 1
|
|
Results
|
Specimen
1B:
embryonic day 12.5; Sim1tm1Fan/Sim1 +
(more )
Specimen
1B:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Fan/Sim1+
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
1B
|
Expression was detected in the anterior hypothalamus but was absent from the most ventral aspect.
|
Specimen
2A:
embryonic day 12.5
(more )
Specimen
2A:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
2A
|
Expression was detected in the anterior hypothalamus.
|
TS20: hypothalamus mantle layer |
Present |
Regionally restricted |
2A
|
Expression was detected in the mantle layer of the anterior hypothalamus in medial and lateral domains that extend from the ventricular layer to the surface of the brain.
|
Specimen
2E:
embryonic day 12.5
(more )
Specimen
2E:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
2E
|
Expression was detected in the anterior hypothalamus.
|
TS20: hypothalamus mantle layer |
Present |
Regionally restricted |
2E
|
Expression was detected in the mantle layer of the anterior hypothalamus in medial and lateral domains that extend from the ventricular layer to the surface of the brain.
|
Specimen
2I:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Fan/Sim1tm1Fan
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Weak |
Regionally restricted |
2I
|
Expression was detected in the anterior hypothalamus but the level was decreased in the mutant compared to wild type.
|
Specimen
2M:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Fan/Sim1tm1Fan
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Weak |
Regionally restricted |
2M
|
Expression was detected in the anterior hypothalamus but the level was decreased in the mutant compared to wild type.
|
Specimen
2Q:
embryonic day 12.5
(more )
Specimen
2Q:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
2Q
|
Expression was detected in the anterior hypothalamus.
|
TS20: hypothalamus mantle layer |
Present |
Regionally restricted |
2Q
|
Expression was detected in the mantle layer of the anterior hypothalamus in medial and lateral domains that extend from the ventricular layer to the surface of the brain.
|
Specimen
2S:
embryonic day 12.5
(more )
Specimen
2S:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
2S
|
Expression was detected in the anterior hypothalamus.
|
TS20: hypothalamus mantle layer |
Present |
Regionally restricted |
2S
|
Expression was detected in the mantle layer of the anterior hypothalamus in medial and lateral domains that extend from the ventricular layer to the surface of the brain.
|
Specimen
2U:
embryonic day 12.5
(more )
Specimen
2U:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
2U
|
Expression was detected in the anterior hypothalamus.
|
TS20: hypothalamus mantle layer |
Present |
Regionally restricted |
2U
|
Expression was detected in the mantle layer of the anterior hypothalamus in medial and lateral domains that extend from the ventricular layer to the surface of the brain.
|
Specimen
2X:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Fan/Sim1tm1Fan
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Weak |
Regionally restricted |
2X
|
Expression was detected in the anterior hypothalamus but the level was decreased in the mutant compared to wild type.
|
Specimen
2Z:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Fan/Sim1tm1Fan
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Weak |
Regionally restricted |
2Z
|
Expression was detected in the anterior hypothalamus but the level was decreased in the mutant compared to wild type.
|
Specimen
2AB:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Fan/Sim1tm1Fan
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Weak |
Regionally restricted |
2AB
|
Expression was detected in the anterior hypothalamus but the level was decreased in the mutant compared to wild type.
|
Specimen
3F:
embryonic day 11.0
(more )
Specimen
3F:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 11.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: diencephalon |
Present |
Regionally restricted |
3F
|
Expression in the mantle layer of the anterior hypothalamus extends to the lateral border of the neural tube with a distinct medial boundary.
|
Specimen
4M:
embryonic day 11.5
(more )
Specimen
4M:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 11.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: diencephalon |
Present |
Regionally restricted |
4M
|
Expression was detected in the mantle layer of the anterior hypothalamus in a lateral domain extending to the surface of the neural tube.
|
Specimen
4Q:
embryonic day 11.5
(more )
Specimen
4Q:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 11.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: diencephalon |
Present |
Regionally restricted |
4Q
|
Expression was detected in the mantle layer of the anterior hypothalamus in a lateral domain extending to the surface of the neural tube.
|
Specimen
5M:
embryonic day 12.5
(more )
Specimen
5M:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus mantle layer |
Present |
Regionally restricted |
5M
|
Expression was detected in the mantle layer of the anterior hypothalamus in medial and lateral domains that extend from the ventricular layer to the surface of the brain.
|
Specimen
5Q:
embryonic day 12.5
(more )
Specimen
5Q:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus mantle layer |
Present |
Regionally restricted |
5Q
|
Expression was detected in the mantle layer of the anterior hypothalamus in medial and lateral domains that extend from the ventricular layer to the surface of the brain.
|
Specimen
6A:
embryonic day 12.5
(more )
Note: Specimen was treated with BrdU.
Specimen
6A:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Note:
|
Specimen was treated with BrdU.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
6A
|
Expression was detected in anterior hypothalamus.
|
Specimen
6C:
embryonic day 12.5
(more )
Note: Specimen was treated with BrdU.
Specimen
6C:
(close )
Genetic Background:
|
involves: 129 * C57BL/6
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Note:
|
Specimen was treated with BrdU.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
6C
|
Expression was detected in anterior hypothalamus.
|
Specimen
6E:
embryonic day 12.5; Sim1tm1Fan/ Sim1tm1Fan
(more )
Note: Specimen was treated with BrdU.
Specimen
6E:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Fan/Sim1tm1Fan
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Note:
|
Specimen was treated with BrdU.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
6E
|
Expression was detected in a more narrow domain of the anterior hypothalamus compared to wild type.
|
Specimen
6G:
embryonic day 12.5; Sim1tm1Fan/ Sim1tm1Fan
(more )
Note: Specimen was treated with BrdU.
Specimen
6G:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Fan/Sim1tm1Fan
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Note:
|
Specimen was treated with BrdU.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
6G
|
Expression was detected in a more narrow domain of the anterior hypothalamus compared to wild type.
|
Specimen
6K:
embryonic day 12.5
(more )
Note: Specimen was treated with BrdU.
Specimen
6K:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Note:
|
Specimen was treated with BrdU.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hypothalamus |
Present |
Regionally restricted |
6K
|
Expression was detected in anterior hypothalamus.
|
Specimen
7B:
embryonic day 15.5
(more )
Specimen
7B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Age:
|
embryonic day 15.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: hypothalamus |
Present |
Regionally restricted |
7B
|
Expression was detected in a domain immediately adjacent to the third ventricle, which corresponds to the paraventricular nucleus.
|
Specimen
7F:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Jlmd/Sim1tm1Jlmd
|
Age:
|
embryonic day 15.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: hypothalamus |
Weak |
Regionally restricted |
7F
|
Expression was reduced in the paraventricular and supraoptic nuclei of the mutant compared to wild type. Transcript was detected in a domain located midway between the third ventricle and the surface of the brain.
|
Specimen
7L:
embryonic day 15.5
(more )
Specimen
7L:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Age:
|
embryonic day 15.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: hypothalamus |
Present |
Regionally restricted |
7L
|
Expression was detected in a domain immediately adjacent to the third ventricle, which corresponds to the paraventricular nucleus.
|
Specimen
7P:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Sim1tm1Jlmd/Sim1tm1Jlmd
|
Age:
|
embryonic day 15.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Carnoy's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: hypothalamus |
Weak |
Regionally restricted |
7P
|
Expression was reduced in the paraventricular and supraoptic nuclei of the mutant compared to wild type. Transcript was detected in a domain located midway between the third ventricle and the surface of the brain.
|
|