Gene Expression Data
Assay Details
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Assay
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Reference:
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J:48924
Murgia C, et al., Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain. EMBO J. 1998 Jul 15;17(14):3940-51
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3694728
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Gene symbol:
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Mki67
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Gene name:
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antigen identified by monoclonal antibody Ki 67
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Results
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Specimen
7A beta4 WT Skin:
embryonic day 18.5
(more  )
Specimen
7A beta4 WT Skin:
(close  )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: skin |
Present |
Regionally restricted |
7A WT
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There were 61.7 immunopositive cells per linear millimeter of basement membrane. Expression was detected in both the basal and immediately suprabasal layers.
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Specimen
7A beta4 TL Skin:
embryonic day 18.5; Itgb4tm1Fgg/ Itgb4tm1Fgg
(more )
Note: The specimen is from non-lesional areas of mutant skin.
Specimen
7A beta4 TL Skin:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Itgb4tm1Fgg/Itgb4tm1Fgg
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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The specimen is from non-lesional areas of mutant skin.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: skin |
Present |
Regionally restricted |
7A TL
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There were significantly fewer (33.7) immunopositive cells per linear millimeter of basement membrane of the mutant. Expression was largely restricted to the basal layer.
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Specimen
7A beta4 WT Duodenum:
embryonic day 18.5
(more )
Specimen
7A beta4 WT Duodenum:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: duodenum |
Present |
Regionally restricted |
7A WT
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Expression was detected in the basal portion of most villi. The total number of immunopositive cells per intervillar space was 12.9.
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Specimen
7A beta4 TL Duodenum:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Itgb4tm1Fgg/Itgb4tm1Fgg
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: duodenum |
Present |
Regionally restricted |
7A TL
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Expression was largely restricted to the intervillar spaces. The total number of immunopositive cells (8.2) per intervillar space was lower than in wild type.
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Analysis Tools