About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:59317 Roth KA, et al., Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):466-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3664066
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-CM1
Detection system: Secondary antibody
Results
Specimen 1e: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 1e Expression is throughout the neuroepithelial wall including the proliferative ventricular zone.

Specimen 1f: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon lamina terminalis Strong 1f

Specimen 4c: embryonic day 12.5; Bcl2l1tm1Dlo/Bcl2l1tm1Dlo (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 4c

Specimen 4d: embryonic day 12.5; Bcl2l1tm1Dlo/Bcl2l1tm1Dlo, Casp3tm1Flv/Casp3tm1Flv (more )
Structure Level Pattern Image Note
TS20: spinal cord Absent 4d

Specimen Table 2 liver: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Present Single cells Less than 1 cell/field was found to be positive.

Specimen Table 2 liver: embryonic day 12.5; Bcl2l1tm1Dlo/Bcl2l1tm1Dlo (more )
Structure Level Pattern Image Note
TS20: liver Present Single cells Less than 1 cell/field was found to be positive. Expression in this mutant is the same as in wild-type embryos.

Specimen Table 2 liver: embryonic day 12.5; Casp3tm1Flv/Casp3tm1Flv (more )
Structure Level Pattern Image Note
TS20: liver Present Single cells Less than 1 cell/field was found to be positive. Expression in this mutant is the same as in wild-type embryos.

Specimen Table 2 liver: embryonic day 12.5; Bcl2l1tm1Dlo/Bcl2l1tm1Dlo, Casp3tm1Flv/Casp3tm1Flv (more )
Structure Level Pattern Image Note
TS20: liver Present Single cells Less than 1 cell/field was found to be positive. Expression in this mutant is the same as in wild-type embryos.

Specimen Table 2 DRG: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present Single cells Only few cells/field stain positive.

Specimen Table 2 DRG: embryonic day 12.5; Bcl2l1tm1Dlo/Bcl2l1tm1Dlo (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present Single cells There is an icrease in the number of positive cells/field.

Specimen Table 2 DRG: embryonic day 12.5; Casp3tm1Flv/Casp3tm1Flv (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Absent

Specimen Table 2 DRG: embryonic day 12.5; Bcl2l1tm1Dlo/Bcl2l1tm1Dlo, Casp3tm1Flv/Casp3tm1Flv (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present Single cells Less than 1 cell/field was found to be positive.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/21/2024
MGI 6.23
The Jackson Laboratory