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Gene Expression Data
Assay Details
Assay
Reference: J:105240 Anttonen AK, et al., The gene disrupted in Marinesco-Sjogren syndrome encodes SIL1, an HSPA5 cochaperone. Nat Genet. 2005 Dec;37(12):1309-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3655497
Gene symbol: Hspa5
Gene name: heat shock protein 5
Antibody: anti-HSPA5
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: This data is pictured in the supplementary material.
Results
Specimen S5b,d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle epithelium Present S5d , S5b
TS20: retina Present S5d , S5b

Specimen S5f: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present S5f There is diffuse expression in the developing cerebral cortex.

Specimen S5h: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: neocortex layer Present S5h Expression is present in cortical neurons.

Specimen S5j,l: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present S5j
TS28: cerebellum Purkinje cell layer Present S5j , S5l
TS28: cerebellum white matter Present S5j Expression is present in the glial cells of the white matter.

Specimen not shown: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Occasional immunopositive granule cells are seen.

Specimen S5n,p: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present S5n Expression is uniform in pyramidal neurons of hippocampal regions.
TS28: hippocampus CA4 Present S5n Expression is uniform in pyramidal neurons of hippocampal regions.
TS28: hippocampus pyramidal cell layer Present S5n Expression is uniform in pyramidal neurons of hippocampal regions.
TS28: hippocampus CA2 Present S5n , S5p Expression is uniform in pyramidal neurons of hippocampal regions.
TS28: hippocampus CA3 Present S5n , S5p Expression is uniform in pyramidal neurons of hippocampal regions.
TS28: dentate gyrus Present S5n


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory