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Gene Expression Data
Assay Details
Assay
Reference: J:16043 Elbling L, et al., P-glycoprotein regulates chemosensitivity in early developmental stages of the mouse. FASEB J. 1993 Dec;7(15):1499-506
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3655164
Gene symbol: Abcb1b
Gene name: ATP-binding cassette, sub-family B member 1B
Antibody: C219 monoclonal
Detection system: Secondary antibody coupled to fluorescein
Assay notes: Embryos were subjected to extensive preparation procedures, which included fixation in 3.7% formol.
Results
Specimen 1A: postnatal (more )
Note: This oocyte is at primary follicle stage.
Structure Level Pattern Image Note
TS28: primary oocyte Present Uniform 1A fluorescence/phase Staining is prominent, uniform, and membranous.
TS28: ovary stratum granulosum Absent 1A fluorescence/phase There is no staining in the granulosa cells.
Specimen 1B: postnatal (more )
Note: This oocyte is at germinal vesicle stage.
Structure Level Pattern Image Note
TS28: primary oocyte Present Uniform 1B Staining is prominent, uniform, and membranous.
Specimen 1C: postnatal (more )
Note: This oocyte is at metaphase I.
Structure Level Pattern Image Note
TS28: primary oocyte Present Uniform 1C Staining is prominent, uniform, and membranous.
Specimen 1D: postnatal (more )
Note: This oocyte is at fertilization; it's at metaphase II and the sperm has penetrated.
Structure Level Pattern Image Note
TS28: secondary oocyte Present Uniform 1D Staining is prominent, uniform, and membranous.
Specimen 1E: embryonic day 0.5 (more )
Note: This zygote is at pronuclear stage.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Uniform 1E Staining is prominent, uniform, and membranous.
Specimen 1F: embryonic day 1.0 (more )
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present Uniform 1F fluorescence/phase Staining is prominent, uniform, and membranous.
Specimen 1G: embryonic day 2.0 (more )
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present Uniform 1G Staining is prominent, uniform, and membranous.
Specimen 1H: embryonic day 2.5 (more )
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Uniform 1H Staining is prominent, uniform, and membranous.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory