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Gene Expression Data
Assay Details
Assay
Reference: J:108109 Oxburgh L, et al., TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605
Assay type: RNA in situ
MGI Accession ID: MGI:3654444
Gene symbol: Wt1
Gene name: WT1 transcription factor
Results
Specimen 4E, 4E': embryonic day 14.5 (more )
Note: Fig. 4E' is a higher magnification of Fig. 4E.
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present Regionally restricted 4E' , 4E Expression was detected in nephrogenic mesenchyme surrounding collecting duct tips.
TS22: maturing glomerular tuft Present Regionally restricted 4E' , 4E Expression was detected in the podocyte layer.
Specimen 4F, 4F': embryonic day 14.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant. Fig. 4F' is a higher magnification of Fig. 4F.
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Absent 4F , 4F'
TS22: renal cortex Present Uniform 4F , 4F' Expression is detected throughout the cortical layer.
TS22: maturing glomerular tuft Present 4F , 4F' Glomerular expression in the podocytes appears normal.
Specimen 4I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present Regionally restricted 4I Expression was detected in nephrogenic mesenchyme.
Specimen 4J: embryonic day 14.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: renal cortex Present 4J Expression was detected in the expanded cortical layer of the mutant.
Specimen 4M: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: metanephros Present 4M
Specimen 4N: embryonic day 16.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: renal cortex Absent 4N
Specimen 5A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present 5A
Specimen 5B: embryonic day 11.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present 5B Expression was detected as in wild type.
Specimen 5I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mesenchyme of metanephros Present 5I Expression was widespread in mesenchyme and marks the condensing mesenchyme around collecting duct tips.
Specimen 5J: embryonic day 12.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: mesenchyme of metanephros Present Diffuse 5J Expression was distributed diffusely throughout the mesenchyme, and few foci of nephrogenic mesenchyme are seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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