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Gene Expression Data
Assay Details
Assay
Reference: J:108109 Oxburgh L, et al., TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605
Assay type: RNA in situ
MGI Accession ID: MGI:3654337
Gene symbol: Pax2
Gene name: paired box 2
Results
Specimen 4C, 4C': embryonic day 14.5 (more )
Note: Fig. 4C' is a higher magnification of Fig. 4C.
Structure Level Pattern Image Note
TS22: collecting duct Present 4C' , 4C Expression was detected throughout the collecting ducts.
TS22: mesenchyme of metanephros Present Regionally restricted 4C' , 4C Expression was detected in nephrogenic mesenchyme surrounding collecting duct tips.
Specimen 4D, 4D': embryonic day 14.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant. Fig. 4D' is a higher magnification of Fig. 4D.
Structure Level Pattern Image Note
TS22: collecting duct Present 4D , 4D' Expression was detected throughout the collecting ducts as in wild type.
TS22: mesenchyme of metanephros Weak Patchy 4D' , 4D Expression was weak and patchy in the nephrogenic mesenchyme surrounding the collecting duct tips.
Specimen 5C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present 5C
Specimen 5D: embryonic day 11.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present 5D Expression was detected as in wild type.
Specimen 5K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mesenchyme of metanephros Present Regionally restricted 5K Expression was detected in nephrogenic mesenchyme. A negative layer of cells surrounds nephrogenic mesenchyme aggregates.
Specimen 5L: embryonic day 12.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: mesenchyme of metanephros Present Regionally restricted 5L Pax2 positive cells appear disorganized in mutant kidneys with large expanses of the mesenchyme devoid of expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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