Gene Expression Data
Assay Details
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Assay
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Reference:
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J:103174
Herrera VL, et al., Embryonic lethality in Dear gene-deficient mice: new player in angiogenesis. Physiol Genomics. 2005 Nov 17;23(3):257-68
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3653630
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Gene symbol:
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Acta2
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Gene name:
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actin alpha 2, smooth muscle, aorta
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Results
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Specimen
3D +/+ embryo:
embryonic day 12.5
(more  )
Specimen
3D +/+ embryo:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: embryo |
Present |
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3D +/+ embryo
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Specimen
3D -/- embryo:
(close )
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Genetic Background:
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B6.Cg-Fbxw7as1tm1Opaz
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Mutant Allele(s):
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Fbxw7as1tm1Opaz/Fbxw7as1tm1Opaz
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: embryo |
Present |
Patchy |
3D -/- embryo
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Scattered expression was detected in the mutant. Expression was strong in the embryo-placenta vascular connection.
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Specimen
3D +/+ angiog:
embryonic day 12.5
(more )
Specimen
3D +/+ angiog:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: blood vessel |
Present |
Regionally restricted |
3D +/+ angiog
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Expression was detected during angiogenesis in the perineural region.
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Specimen
3D -/- angiog:
(close )
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Genetic Background:
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B6.Cg-Fbxw7as1tm1Opaz
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Mutant Allele(s):
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Fbxw7as1tm1Opaz/Fbxw7as1tm1Opaz
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: blood vessel |
Present |
Regionally restricted |
3D -/- angiog
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Expression was detected during angiogenesis in the perineural region as in wild type, but there was less branching in the mutant.
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Specimen
3D +/+ vasc net:
embryonic day 12.5
(more )
Specimen
3D +/+ vasc net:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: embryo |
Present |
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3D +/+ vasc net
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Specimen
3D -/- vasc net:
(close )
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Genetic Background:
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B6.Cg-Fbxw7as1tm1Opaz
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Mutant Allele(s):
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Fbxw7as1tm1Opaz/Fbxw7as1tm1Opaz
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: embryo |
Present |
Regionally restricted |
3D -/- vasc net
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Expression was detected in sporadic blood islands incompletely circumscribed by immunostained single cell vascular wall in the mutant.
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Analysis Tools