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Gene Expression Data
Assay Details
Assay
Reference: J:107595 Landsberg RL, et al., Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6. Neuron. 2005 Dec 22;48(6):933-47
Assay type: RNA in situ
MGI Accession ID: MGI:3639903
Gene symbol: Neurog1
Gene name: neurogenin 1
Probe: Ngn1 probe1
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 2M: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 2M Expression was detected in lower rhombic lip progenitor cells.

Specimen 2N: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2N Expression was detected in lower rhombic lip progenitor cells.

Specimen 2O and inset: embryonic day 12.5 (more )
Note: Inset is a lower magnification view.
Structure Level Pattern Image Note
TS20: hindbrain Weak Regionally restricted 2O Expression was detected in lower rhombic lip progenitor cells. Expression levels in the lower rhombic lip were diminished compared to the earlier time points, but ventral expression remained robust.

Specimen 2P: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube Present 2P

Specimen 2W: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2W Expression in the dorsal hindbrain was detectable caudal but not rostral to the Rhombomere(r)6/r7 boundary.

Specimen 2X: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2X Expression in the dorsal hindbrain was detectable caudal but not rostral to the Rhombomere(r)6/r7 boundary.

Specimen 5C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 5C Expression was detected in lower rhombic lip.

Specimen 5D: embryonic day 10.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 5D Expression was detected in lower rhombic lip as in wild type.

Specimen 5G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 5G Expression was detected in lower rhombic lip.

Specimen 5H: embryonic day 11.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 5H Expression was expanded in lower rhombic lip in mutant compared to wild type.

Specimen 5K and inset: embryonic day 12.5 (more )
Note: Inset is a lower magnification view.
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 5K Expression was largely absent in lower rhombic lip but was detected in the ventral hindbrain.

Specimen 5L and inset: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Note: Inset is a lower magnification view.
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 5L Expression was detected in lower rhombic lip in mutant compared to wild type. Expression was detected in ventral hindbrain.

Specimen 6L inset: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Note: Also stained for Pou4f1 (Brn3a; assay MGI:3639919).
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 6L inset Expression was detected in lower rhombic lip.

Specimen S1I: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted S1I Expression was detected in lower rhombic lip.

Specimen S1K: embryonic day 11.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted S1K Expression was expanded in lower rhombic lip in mutant compared to wild type.

Specimen S1J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted S1J Expression was detected in lower rhombic lip.

Specimen S1L: embryonic day 11.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted S1L Expression was expanded in lower rhombic lip in mutant compared to wild type.

Specimen S1M: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted S1M Expression was detected in lower rhombic lip but was lower than at E11.5.

Specimen S1O: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted S1O Expression was expanded in lower rhombic lip in mutant compared to wild type.

Specimen S1N: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted S1N Expression was detected in lower rhombic lip but was lower than at E11.5.

Specimen S1P: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted S1P Expression was expanded in lower rhombic lip in mutant compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory