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Gene Expression Data
Assay Details
Assay
Reference: J:106710 Takemoto M, et al., Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J. 2006 Mar 8;25(5):1160-74
Assay type: RNA in situ
MGI Accession ID: MGI:3625923
Gene symbol: Ren1
Gene name: renin 1 structural
Probe: Ren1 probe1
Probe preparation: Antisense RNA
Results
Specimen 3B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: renal cortex Present Regionally restricted 3B Ren1 Expression is in glomerular mesangial cells.
Specimen 3D Comma: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: comma-shaped body Absent 3D Ren1 Comma Expression is absent in the comma-shaped stage of nephron development.
Specimen 3D S-shaped: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: s-shaped body Absent 3D Ren1 S-shaped Expression is absent in the S-shaped stage of nephron development.
Specimen 3D Capillary loop: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: presumptive mesangium of capillary loop renal corpuscle Present Regionally restricted 3D Ren1 Capill loop Expression is in mesangial cells.
TS26: capillary loop renal corpuscle Present Regionally restricted 3D Ren1 Capill loop Expression also noticed in smooth muscle cells of glomerular afferent and efferent arterioles.
Specimen 3D Mature: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: glomerular mesangium of glomerular tuft Present Regionally restricted 3D Ren1 Mature Expression is in mesangial cells.
TS26: afferent arteriole of mature renal corpuscle Present Regionally restricted 3D Ren1 Mature Expression also noticed in smooth muscle cells of glomerular afferent and efferent arterioles.
TS26: efferent arteriole of mature renal corpuscle Present Regionally restricted 3D Ren1 Mature Expression also noticed in smooth muscle cells of glomerular afferent and efferent arterioles.
Specimen 5B +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: capillary loop renal corpuscle Present 5B Ren1 +/+
Specimen 5B -/-: embryonic day 18.5; Foxc2tm1Miu/Foxc2tm1Miu (more )
Structure Level Pattern Image Note
TS26: capillary loop renal corpuscle Present 5B Ren1 -/- Expression is present but the distribution is abnormal in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory