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Gene Expression Data
Assay Details
Assay
Reference: J:105958 Chen J, et al., Expression of Notch signaling pathway genes in mouse embryos lacking beta4galactosyltransferase-1. Gene Expr Patterns. 2006 Apr;6(4):376-82
Assay type: RNA in situ
MGI Accession ID: MGI:3620811
Gene symbol: Hes5
Gene name: hes family bHLH transcription factor 5
Probe: Hes5 cDNA6
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1 Normal, +/?: embryonic day 9.5 (more )
Note: Wild-type embryos are either heterozygotes or +/+.
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Present Regionally restricted 1_Normal The majority of embryos (14/19) showed expression in the posterior half of the forming somite and/or the presomitic mesoderm.
TS15: trunk somite Present Regionally restricted 1_Normal The majority of embryos (14/19) showed expression in the posterior half of the forming somite and/or the presomitic mesoderm.
TS15: neural tube Strong 1_Normal
TS15: tail neural tube Strong 1_Normal

Specimen +/-: embryonic day 9.5; B4galt1tm1Shur/B4galt1+ (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Present Regionally restricted Expression in heterozygotes is the same as in wild-type embryos. The majority of embryos (14/19) showed expression in the posterior half of the forming somite and/or the presomitic mesoderm.
TS15: trunk somite Present Regionally restricted Expression in heterozygotes is the same as in wild-type embryos. The majority of embryos (14/19) showed expression in the posterior half of the forming somite and/or the presomitic mesoderm.
TS15: neural tube Strong Expression in heterozygotes is the same as in wild-type embryos.
TS15: tail neural tube Strong Expression in heterozygotes is the same as in wild-type embryos.

Specimen 1 Low, -/-: embryonic day 9.5; B4galt1tm1Shur/B4galt1tm1Shur (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Trace Regionally restricted 1_Low Expression is in the posterior half of the forming somite.
TS15: trunk somite Trace Regionally restricted 1_Low Expression is in the posterior half of the forming somite.
TS15: neural tube Strong 1_Low
TS15: tail neural tube Strong 1_Low

Specimen 1 None, -/-: embryonic day 9.5; B4galt1tm1Shur/B4galt1tm1Shur (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Absent 1_None
TS15: trunk somite Absent 1_None
TS15: neural tube Strong 1_None
TS15: tail neural tube Strong 1_None


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory