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Gene Expression Data
Assay Details
Assay
Reference: J:104158 Alanentalo T, et al., Cloning and analysis of Nkx6.3 during CNS and gastrointestinal development. Gene Expr Patterns. 2006 Jan;6(2):162-70
Assay type: RNA in situ
MGI Accession ID: MGI:3614855
Gene symbol: Nkx6-2
Gene name: NK6 homeobox 2
Probe: Nkx6-2 cDNA1
Probe preparation: Antisense RNA
Results
Specimen 4B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present Regionally restricted 4B Expression is in the dorsal and ventral pancreatic buds, absent in stomach or duodenal endoderm.
Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: foregut-midgut junction Present Regionally restricted 4E Expression is in the pancreatic epithelium and the developing duodenum.
TS17: pancreas primordium Present Regionally restricted 4E Expression is in the pancreatic epithelium and the developing duodenum.
TS17: stomach Present Regionally restricted 4E
Specimen 4H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: foregut-midgut junction Present Regionally restricted 4H Expression is in the pancreatic epithelium and the developing duodenum.
TS17: pancreas primordium Present Regionally restricted 4H Expression is in the pancreatic epithelium and the developing duodenum.
TS17: stomach Present Regionally restricted 4H
Specimen 4K: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas Present 4K
Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach glandular region epithelium Present Regionally restricted 5B Expression is in the caudal stomach.
Specimen 5E,H: embryonic day 16.5 (more )
Note: (G)-(I) shows high magnification of the glandular stomach and duodenum (inset) seen in (D)-(F).
Structure Level Pattern Image Note
TS24: stomach glandular region Present Regionally restricted 5E , 5H Expression is at the base of the gastric units.
TS24: duodenum Present Regionally restricted 5E Expression is in the transitional zone between the stomach and doudenum.
TS24: stomach Present Regionally restricted 5E Expression is in the transitional zone between the stomach and doudenum.
Specimen 5H inset: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: duodenum Present Regionally restricted 5H inset Expression is in the transitional zone between the stomach and doudenum.
Specimen 5K: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: stomach Present Regionally restricted 5K Expression is at the base of the gastric units.
Specimen 5N: postnatal adult (more )
Structure Level Pattern Image Note
TS28: stomach Present Regionally restricted 5N Expression is at the base of the gastric units.
Specimen 6B: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: stomach Present Regionally restricted 6B Expression is predominantly in the crypts of the gastric units.
Specimen S2A: embryonic day 14.5 (more )
Note: Double labeled: red - Nkx6-2; green - Nkx6-1 (assay MGI:3614671).
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted S2_A Mutually exclusive expression in the dorsal pancreas with Nkx6.1.
Specimen S2B: embryonic day 14.5 (more )
Note: Double labeled: red - Nkx6-2; green - Isl1 (assay MGI:3616019).
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted S2_B Expression is in the dorsal pancreas and is absent in endocrine cells.
Specimen Not Shown: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: pancreas Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory