Gene Expression Data
Assay Details
Assay
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Reference:
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J:48518
Kusumi K, et al., The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries. Nat Genet. 1998 Jul;19(3):274-8
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3612134
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Gene symbol:
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Meox1
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Gene name:
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mesenchyme homeobox 1
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Probe:
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Meox1 cDNA1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
pu/+:
embryonic day 9.5; Dll3pu/Dll3 +
(more )
Specimen
pu/+:
(close )
Genetic Background:
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involves: 101/Rl * C3H/Rl
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Mutant Allele(s):
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Dll3pu/Dll3+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS15: trunk somite |
Present |
Graded |
3l
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Expression is stronger in the caudal section of each somite.
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Specimen
pu/pu:
(close )
Genetic Background:
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involves: 101/Rl * C3H/Rl
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Mutant Allele(s):
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Dll3pu/Dll3pu
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS15: trunk somite |
Present |
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3m
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The strong caudal expression seen in wild type animals is disrupted in the mutants, and the somites appear irregular in size and shape.
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