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Gene Expression Data
Assay Details
Assay
Reference: J:99372 van der Zwaag B, et al., Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. Genomics. 2005 Jul;86(1):55-67
Assay type: RNA in situ
MGI Accession ID: MGI:3605537
Gene symbol: Tmcc1
Gene name: transmembrane and coiled coil domains 1
Probe: Kiaa0779 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: After cryosectioning, tissue was fixed for 10' in 4% paraformaldehyde. The author divided the genes analyzed in this publication into 4 groups based on their expression patterns. The expression pattern of this gene was placed in group 4 (See Table 1).
Results
Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Weak Non-Uniform 5A
TS20: brain Present 5A
TS20: central nervous system ganglion Present 5A
TS20: spinal cord Present Regionally restricted 5A Expression was detected in the ventral side of the neural tube.

Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 5B

Specimen 5C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cranial ganglion Present 5C
TS22: facial ganglion Present 5C
TS22: facial nerve Present 5C

Specimen 5D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindbrain Present Regionally restricted 5D Expression was detected in the facial nucleus.

Specimen 5E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hindbrain Present Regionally restricted 5E Expression was detected in the facial nucleus.
TS24: dorsal root ganglion Present 5E

Specimen 5F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: olfactory epithelium Present 5F
TS26: olfactory lobe Present Regionally restricted 5F Expression was detected in the olfactory bulb.

Specimen not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain Weak
TS26: hindbrain Absent
TS26: cerebral cortex Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory