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Gene Expression Data
Assay Details
Assay
Reference: J:57798 Monaghan AP, et al., Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev. 1999 Sep;87(1-2):45-56
Assay type: RNA in situ
MGI Accession ID: MGI:3603190
Gene symbol: Dkk3
Gene name: dickkopf WNT signaling pathway inhibitor 3
Probe: mdkk3 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: bulbus cordis Present 4D Expression is present in myocardial cells of the developing ventricles in the cells of the bulbus cordis.
TS17: sinus venosus Present 4D Expression is present in myocardial cells of the developing ventricles in the cells of the bulbus cordis.
TS17: head mesenchyme Present 4D Expression is present in the head mesoderm of the fronto-nasal prominence.
TS17: 1st branchial arch Absent 4D

Specimen 4I: embryonic day 12.0-12.5 (more )
Structure Level Pattern Image Note
TS20: endocardial cushion Strong 4I Expression is found in the cushions that develop in the atrioventricular and truncoconal region.
TS20: dorsal aorta Strong 4I
TS20: heart Strong 4I Expression is present in the aortic valve area.
TS20: pulmonary artery Weak 4I
TS20: left atrium Present Regionally restricted 4I Expression is present in the ventral walls.
TS20: right atrium Present Regionally restricted 4I Expression is present in the ventral walls.
TS20: blood vessel Present 4I Expression is present in emerging blood vessels.
TS20: lung Present Regionally restricted 4I Expression is present in cells condensing around the main branches of the bronchus.

Specimen 5K: embryonic day 9.5-10.0 (more )
Structure Level Pattern Image Note
TS15: limb Absent 5K

Specimen 5N: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb mesenchyme Present 5N Expression is present in mesenchymal condensations around bone primordia. It is absent from medial regions of developing bone.

Specimen 5Q: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb mesenchyme Present 5Q Expression is present in mesenchymal condensations around bone primordia. It is absent from medial regions of developing bone.

Specimen 6D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nose Present Regionally restricted 6D Expression is present in mesoderm derived cells in the nasal capsule.
TS20: primary palate Moderate 6D
TS20: cartilage Present 6D
TS20: vibrissa Weak 6D
TS20: head mesenchyme Weak 6D Expression is present in mesoderm adjacent to hair or whisker follicles.

Specimen 6H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: head mesenchyme Strong Regionally restricted 6H There is strong expression in mesenchyme adjacent to developing teeth.
TS20: primary palate Weak 6H There is weak expression in the palate.

Specimen 8C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 8C Expression is present in the ventral diencephalon.
TS17: midbrain Weak Regionally restricted 8C Expression is present in the cranial flexure.

Specimen 8F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Present 8F

Specimen Not shown--E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pericardial component Strong Strong expression is present in the pericardial sac.
TS20: intraembryonic coelom Present Regionally restricted Expression is present in the mesenchyme of the developing diaphragm.
TS20: peritoneal component Present
TS20: telencephalon ventricular layer Present
TS20: spinal cord ventricular layer Present Regionally restricted Expression is present in the ventricular zone in the basal half of the neural tube.
TS20: spinal cord roof plate Present

Specimen Not shown--E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: embryo mesenchyme Trace Expression is barely detectable in undifferentiated lateral mesenchymal cells in the body and limbs.
TS23: limb mesenchyme Trace Expression is barely detectable in undifferentiated lateral mesenchymal cells in the body and limbs.

Specimen Table 1: postnatal (more )
Structure Level Pattern Image Note
TS28: decidua Absent

Specimen Table 1--Bone E15: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: skeleton Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory