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Gene Expression Data
Assay Details
Assay
Reference: J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
Assay type: RNA in situ
MGI Accession ID: MGI:3586166
Gene symbol: Dkk3
Gene name: dickkopf WNT signaling pathway inhibitor 3
Probe: UI-M-AL0-abx-a-08-0-UI.s1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: This data is from Supplemental Table 5, Gene column, row: 55143 Dickkopf homolog 3 . After cryosectioning, tissue was fixed for 10' in 4% paraformaldehyde prior to processing.
Results
Specimen E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Present Regionally restricted 5B Dkk3 E14 , Submitted Image - Dkk3e14d , Submitted Image - Dkk3e14. , Submitted Image - Dkk3e14 Expression was detected in the outer neuroblastic layer but was higher in a subset of cells.
Specimen E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: retina nuclear layer Present Regionally restricted Submitted Image - Dkk3e16 , Submitted Image - Dkk3e16. , 5B Dkk3 E16 , Submitted Image - Dkk3e16b Expression was detected in the outer neuroblastic layer.
Specimen E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: retina outer nuclear layer Present Submitted Image - Dkk3e18 , Submitted Image - Dkk3e18p , 5B Dkk3 E18 Expression was detected in the outer neuroblastic layer.
Specimen P0/1: postnatal day 0-1 (more )
Structure Level Pattern Image Note
TS27: retina outer nuclear layer Present Regionally restricted Submitted Image - Dkk3p0b , Submitted Image - Dkk3p0 , 5B Dkk3 P0 Expression was detected in the vitreal outer neuroblastic layer.
Specimen P2/3: postnatal day 2-3 (more )
Structure Level Pattern Image Note
TS27: retina outer nuclear layer Present Regionally restricted Submitted Image - Dkk3p2 , 5B Dkk3 P2 Expression was detected in the vitreal outer neuroblastic layer.
Specimen P4/5: postnatal day 4-5 (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Regionally restricted Submitted Image - Dkk3p4b , 5B Dkk3 P4 , Submitted Image - Dkk3p4 Expression was detected in the vitreal outer neuroblastic layer.
Specimen P6/7: postnatal day 6-7 (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present 5B Dkk3 P6 Expression was detected in the inner nuclear layer and tentatively in the Muller glia.
Specimen P8/10: postnatal day 8-10 (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Strong Submitted Image - Dkk3p8 , Submitted Image - Dkk3p8b , Submitted Image - Dkk3p8 Expression was detected in the inner nuclear layer and tentatively in Muller glia.
Specimen Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 5B Dkk3 Adult Expression was detected in the Muller glia.
Specimen CNS: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: brain subventricular zone Present
Specimen Embryo: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted Expression was detected in the subventricular zone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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