About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:95901 Li Q, et al., A targeted mutation of Nkd1 impairs mouse spermatogenesis. J Biol Chem. 2005 Jan 28;280(4):2831-9
Assay type: Western blot
MGI Accession ID: MGI:3583351
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: 8E4
Assay notes: Testes were fractionated into germ-, Leydig-, and Sertoli cell fractions.
Results
Image: 5D ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
Germ, +/+ P adult TS28: germ cell of testis Present Not Specified Male
Germ, +/- P adult TS28: germ cell of testis Present involves: 129X1/SvJ Nkd1tm1Tko/Nkd1+Male
Germ, -/- P adult TS28: germ cell of testis Present (a) involves: 129X1/SvJ Nkd1tm1Tko/Nkd1tm1TkoMale
Leydig, +/+ P adult TS28: interstitium of the testis Present Not Specified Male
Leydig, +/- P adult TS28: interstitium of the testis Present involves: 129X1/SvJ Nkd1tm1Tko/Nkd1+Male
Leydig, -/- P adult TS28: interstitium of the testis Present involves: 129X1/SvJ Nkd1tm1Tko/Nkd1tm1TkoMale
Sertoli, +/+ P adult TS28: seminiferous tubule Present Not Specified Male
Sertoli, +/- P adult TS28: seminiferous tubule Present involves: 129X1/SvJ Nkd1tm1Tko/Nkd1+Male
Sertoli, -/- P adult TS28: seminiferous tubule Present involves: 129X1/SvJ Nkd1tm1Tko/Nkd1tm1TkoMale
Notes:
(a) There was an increase in levels in germ cells. Quantification is shown in Figure 5E and shows that there is a 1.7fold increase.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory