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Gene Expression Data
Assay Details
Assay
Reference: J:98379 Zakin L, et al., Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development. 2005 May;132(10):2489-99
Assay type: RNA in situ
MGI Accession ID: MGI:3582814
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Results
Specimen 6E: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 6E Expression was detected in the allantois.
TS14: mesenchyme derived from lateral plate Present 6E
TS14: tail bud Present 6E
Specimen 6E': embryonic day 9.0; Twsg1tm1Emdr/Twsg1tm1Emdr, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 6E' As in wild type, expression was detected in the allantois.
TS14: mesenchyme derived from lateral plate Present 6E' Expression was detected as in wild type.
TS14: tail bud Weak Regionally restricted 6E' Expression was reduced compared to wild type in the region closest to the tip of the tail.
Specimen 6F: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 6F Expression was detected in the allantois.
TS14: tail bud Present 6F
Specimen 6F': embryonic day 9.0; Twsg1tm1Emdr/Twsg1tm1Emdr, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 6F' As in wild type, expression was detected in the allantois.
TS14: tail bud Weak Regionally restricted 6F' Expression was reduced compared to wild type in the region closest to the tip of the tail.
Specimen 7A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo ectoderm Present Regionally restricted 7A Expression was detected in the ventrolateral part of the embryo in ectoderm.
TS15: hindlimb ridge mesenchyme Present 7A
TS15: trunk mesenchyme Present Regionally restricted 7A Expression was detected in lateral plate mesoderm.
Specimen 7A': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: hindlimb ridge mesenchyme Present 7A' Expression in the wild type is seen as 2 lateral domains.
TS15: embryo mesenchyme Present Regionally restricted 7A' Expression was detected in ventral mesoderm.
Specimen 7B: embryonic day 9.5; Twsg1tm1Emdr/Twsg1tm1Emdr, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS15: embryo Present 7B
Specimen 7B': embryonic day 9.5; Twsg1tm1Emdr/Twsg1tm1Emdr, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS15: hindlimb ridge mesenchyme Present 7B' Expression was detected in a transverse horizontal domain in the mutant, instead of the 2 lateral ones on the right and left hindlimb buds seen in the wild type.
TS15: embryo mesenchyme Present Regionally restricted 7B' Expression in the ventral most mesoderm forms a separate domain in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory