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Gene Expression Data
Assay Details
Assay
Reference: J:98379 Zakin L, et al., Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development. 2005 May;132(10):2489-99
Assay type: RNA in situ
MGI Accession ID: MGI:3582813
Gene symbol: Shh
Gene name: sonic hedgehog
Results
Specimen 7E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present Regionally restricted 7E Expression was detected in the zone of polarizing activity.
TS17: hindgut Present Regionally restricted 7E Expression was detected in the hindgut endoderm.
TS17: notochord Present 7E

Specimen 7E': embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present Regionally restricted 7E' Expression was detected in the zone of polarizing activity.
TS17: hindgut Present Regionally restricted 7E' Expression was detected in the hindgut endoderm.
TS17: notochord Present 7E'

Specimen 7F: embryonic day 10.5; Twsg1tm1Emdr/Twsg1tm1Emdr, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Absent 7F Expression was delayed in the mutant zone of polarizing activity.
TS17: hindgut Weak Regionally restricted 7F Expression was weak in the mutant hindgut endoderm.
TS17: notochord Present 7F Expression was detected as in wild type.

Specimen 7F': embryonic day 10.5; Twsg1tm1Emdr/Twsg1tm1Emdr, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Absent 7F' Expression was delayed in the mutant zone of polarizing activity.
TS17: hindgut Weak Regionally restricted 7F' Expression was weak in the mutant hindgut endoderm.
TS17: notochord Present 7F' Expression was detected as in wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory