About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:98379 Zakin L, et al., Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development. 2005 May;132(10):2489-99
Assay type: RNA in situ
MGI Accession ID: MGI:3582812
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Results
Specimen 6B: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS13: primitive streak Present 6B
TS13: trunk mesenchyme Present Regionally restricted 6B Expression was detected in the posterior mesoderm.
Specimen 6B': embryonic day 8.25; Twsg1tm1Emdr/Twsg1+, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS13: primitive streak Weak 6B' Staining was fainter in the mutant.
TS13: trunk mesenchyme Weak Regionally restricted 6B' Staining was fainter in the mutant in the posterior mesoderm.
Specimen 6C: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 6C Expression was detected in the posterior region of the embryo.
Specimen 6C': embryonic day 8.25; Twsg1tm1Emdr/Twsg1+, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS13: embryo Weak Regionally restricted 6C' Staining was weaker in the posterior region of the mutant embryo.
Specimen 7C: embryonic day 10.5; Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present 7C The apical ectodermal ridge forms 2 lateral arches in the wild type.
Specimen 7C': embryonic day 10.5; Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present 7C' Staining in the mutant adopts a horseshoe like shape, the 2 apical ectodermal ridge regions meet posteriorly.
Specimen 7D: embryonic day 10.5; Twsg1tm1Emdr/Twsg1+, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present 7D Staining of the apical ectodermal ridge forms 2 lateral arches in the wild type.
Specimen 7D': embryonic day 10.5; Twsg1tm1Emdr/Twsg1+, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present 7D' Staining in the mutant adopts a horseshoe like shape, the 2 apical ectodermal ridge regions meet posteriorly.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory