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Gene Expression Data
Assay Details
Assay
Reference: J:89190 Poschl E, et al., Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development. Development. 2004 Apr;131(7):1619-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3576209
Gene symbol: Nid1
Gene name: nidogen 1
Antibody: anti-nidogen 1
Detection system: Secondary antibody
Results
Specimen 3A +/-: embryonic day 10.5; Del(8Col4a1-Col4a2)1Epo/+ (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 3A Nd-1 +/- Expression is detected in the basement membrane, adjacent to epithelia, vascular endothelia, somites, notochord, and the neuroectoderm.

Specimen 3A -/-: embryonic day 10.5; Del(8Col4a1-Col4a2)1Epo/Del(8Col4a1-Col4a2)1Epo (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 3A Nd-1 -/- As in wild-type, expression is detected in the basement membrane, adjacent to epithelia, vascular endothelia, somites, notochord, and the neuroectoderm. However, the staining appears weaker than what is seen in wild type.

Specimen 3B +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: extraembryonic component Present Regionally restricted 3B Nd-1 +/+ Expression is present in the Reichert's membrane.

Specimen 3B -/-: embryonic day 10.5; Del(8Col4a1-Col4a2)1Epo/+ (more )
Structure Level Pattern Image Note
TS17: extraembryonic component Present Regionally restricted 3B Nd-1 -/- Expression is present in the Reichert's membrane.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory