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Gene Expression Data
Assay Details
Assay
Reference: J:67751 Campione M, et al., Pitx2 expression defines a left cardiac lineage of cells: evidence for atrial and ventricular molecular isomerism in the iv/iv mice. Dev Biol. 2001 Mar 1;231(1):252-64
Assay type: RNA in situ
MGI Accession ID: MGI:3530358
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2 cDNA4
Probe preparation: Antisense RNA
Results
Specimen 4A: embryonic day 8.0 (more )
Note: This embryo contains 2-4 somites.
Structure Level Pattern Image Note
TS12: cardiogenic plate Present Regionally restricted 4A Expression is present on the left side of the cardiac crescent.
Specimen 4C: embryonic day 8.0 (more )
Note: This embryo contains 6-8 somites. This is a ventral view.
Structure Level Pattern Image Note
TS12: common atrial chamber Present 4C Expression is present in the left prospective sinoatrial region.
TS12: primitive ventricle Present 4C Expression is present in the most dorsal part of the left ventricular region.
Specimen 4E: embryonic day 8.0 (more )
Note: This embryo contains 6-8 somites. This is a left view.
Structure Level Pattern Image Note
TS12: common atrial chamber Present 4E Expression is present in the left prospective sinoatrial region.
TS12: primitive ventricle Present 4E Expression is present in the most dorsal part of the left ventricular region.
Specimen 4F: embryonic day 8.0 (more )
Note: This embryo contains 6-8 somites. This is a transverse section.
Structure Level Pattern Image Note
TS12: primitive ventricle Present Regionally restricted 4F Expression is present in the most dorsal part of the left ventricular region.
Specimen 4G: embryonic day 8.25 (more )
Note: This embryo contains 12-14 somites. This is a left lateral view.
Structure Level Pattern Image Note
TS13: common atrial chamber Present Regionally restricted 4G Expression is present in the left portion of the sinoatrial region.
TS13: heart Present Regionally restricted 4G Expression is present along the inner curvature of the heart, including part of the atrioventricular canal.
TS13: primitive ventricle Present 4G Expression is present in prospective left and right ventricles.
TS13: outflow tract Present 4G
TS13: lateral plate mesoderm Present 4G Expression is present in the left lateral plate mesoderm.
Specimen 4H: embryonic day 8.25 (more )
Note: This embryo contains 12-14 somites.
Structure Level Pattern Image Note
TS13: common atrial chamber Present Regionally restricted 4H Expression is present in the left portion of the sinoatrial region.
TS13: heart Present Regionally restricted 4H Expression is present along the inner curvature of the heart, including part of the atrioventricular canal.
TS13: primitive ventricle Present 4H Expression is present in prospective left and right ventricles.
TS13: outflow tract Present 4H
Specimen 5A: embryonic day 10.0 (more )
Note: This is a left lateral view.
Structure Level Pattern Image Note
TS16: common atrial chamber left part Present 5A
TS16: outflow tract Present Regionally restricted 5A Expression is present in the left/ventral portion of the outflow tract, as well as in the mesenchyme that will form the aortic sac.
TS16: primitive ventricle Present Regionally restricted 5A Expression is present in the ventral portion of the left ventricle, beside the interventricular groove.
TS16: atrioventricular canal Present Regionally restricted 5A Expression is present in the anterior part.
Specimen 5B: embryonic day 10.0 (more )
Note: This is a right lateral view.
Structure Level Pattern Image Note
TS16: primitive ventricle Present Regionally restricted 5B Expression is present in the ventral part of the right ventricle.
TS16: common atrial chamber right part Absent 5B
Specimen 5C: embryonic day 10.0 (more )
Note: This is a ventral view.
Structure Level Pattern Image Note
TS16: common atrial chamber left part Present 5C
TS16: common atrial chamber right part Absent 5C
TS16: primitive ventricle Present Regionally restricted 5C Expression is present in the ventral portion of the left ventricle, beside the interventricular groove, and the ventral part of the right ventricle.
TS16: outflow tract Present Regionally restricted 5C Expression is present in the left/ventral portion of the outflow tract.
Specimen 5D: embryonic day 10.0 (more )
Note: This is a transverse section.
Structure Level Pattern Image Note
TS16: common atrial chamber Present Regionally restricted 5D Expression is present in the septum primum.
TS16: common atrial chamber left part Present 5D
TS16: common atrial chamber right part Absent 5D
Specimen 5E: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: primitive ventricle Present Regionally restricted 5E Expression is present in the ventral portion of the left ventricle, beside the interventricular groove, and the ventral part of the right ventricle.
TS16: outflow tract Present Regionally restricted 5E Expression is present in the left/ventral portion of the outflow tract.
Specimen 5F: embryonic day 13.5 (more )
Note: This is a ventral view.
Structure Level Pattern Image Note
TS21: left atrium Present 5F Expression is present in both the dorsal and ventral part of the left atrium.
TS21: right atrium Absent 5F
TS21: heart left ventricle Present Regionally restricted 5F Expression is present in most of the ventral, but not dorsal, region of the left ventricle.
TS21: heart right ventricle Present Regionally restricted 5F Expression is present in the entire ventral, but not dorsal, region of the right ventricle.
TS21: outflow tract Present Regionally restricted 5F Expresson is confined to the ventral, but not dorsal, surface.
Specimen 5G: embryonic day 13.5 (more )
Note: This is a dorsal view.
Structure Level Pattern Image Note
TS21: left atrium Present 5G Expression is present in both the dorsal and ventral part of the left atrium.
TS21: heart left ventricle Present Regionally restricted 5G Expression is present in most of the ventral, but not dorsal, region of the left ventricle.
TS21: heart right ventricle Present Regionally restricted 5G Expression is present in the entire ventral, but not dorsal, region of the right ventricle.
TS21: right atrium Absent 5G
Specimen Not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: heart left ventricle Absent
TS24: heart right ventricle Absent
TS24: aorta Absent There is no expression in the outflow tract.
Specimen Not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: left atrium Weak
Specimen 6A: embryonic day 11.5; Dnah11iv/Dnah11iv (more )
Note: This heart exhibits a d-loop.
Structure Level Pattern Image Note
TS19: left atrium Present 6A
TS19: right atrium Absent 6A
TS19: heart left ventricle Present 6A
TS19: heart right ventricle Present 6A
Specimen 6B: embryonic day 11.5; Dnah11iv/Dnah11iv (more )
Note: This heart exhibits a l-loop.
Structure Level Pattern Image Note
TS19: right atrium Present 6B
TS19: left atrium Absent 6B
TS19: heart left ventricle Present 6B
TS19: heart right ventricle Present 6B
Specimen 6C: embryonic day 11.5; Dnah11iv/Dnah11iv (more )
Note: This heart exhibits a d-loop.
Structure Level Pattern Image Note
TS19: left atrium Present 6C
TS19: right atrium Present 6C
TS19: heart left ventricle Present 6C
TS19: heart right ventricle Present 6C
TS19: atrioventricular canal Present 6C Expression was extended to the ventral region.
Specimen 6D: embryonic day 11.5; Dnah11iv/Dnah11iv (more )
Note: This heart exhibits a l-loop.
Structure Level Pattern Image Note
TS19: left atrium Absent 6D
TS19: right atrium Absent 6D
TS19: heart left ventricle Present 6D
TS19: heart right ventricle Present 6D
Specimen 6E: embryonic day 11.5; Dnah11iv/Dnah11iv (more )
Structure Level Pattern Image Note
TS19: heart right ventricle Present 6E Expression is present in both the dorsal and ventral sides, although the domain of ectopic dorsal expression is not as broad as the normal ventral expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory