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Gene Expression Data
Assay Details
Assay
Reference: J:92194 Li Y, et al., Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis. Dev Biol. 2004 Jun 1;270(1):214-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3526074
Gene symbol: Ccnd2
Gene name: cyclin D2
Antibody: anti-cyclin D2
Detection system: Secondary antibody coupled to alkaline phosphatase
Results
Specimen 4Ad: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present Regionally restricted 4A d High expression, predominantly in proximal epithelium, with lower levels distally.
TS21: lung mesenchyme Present Regionally restricted 4A d Expression throughout mesenchyme, but not in more proximal regions around bronchial smooth muscles.

Specimen 4Ae: embryonic day 13.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present Regionally restricted 4A e Expression levels are comparable to wild-type; the proximal-distal differential distribution in the epithelium is also maintained.
TS21: lung mesenchyme Present Regionally restricted 4A e Expression levels are comparable to wild-type; the proximal-distal differential distribution in the epithelium is also maintained.

Specimen 4Af: embryonic day 13.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present Regionally restricted 4A f Expression levels are comparable to wild-type; the proximal-distal differential distribution in the epithelium is also maintained.
TS21: lung mesenchyme Present Regionally restricted 4A f Expression levels are comparable to wild-type; the proximal-distal differential distribution in the epithelium is also maintained.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory