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Gene Expression Data
Assay Details
Assay
Reference: J:93571 Rowan S, et al., Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development. 2004 Oct;131(20):5139-52
Assay type: RNA in situ
MGI Accession ID: MGI:3525844
Gene symbol: Vsx2
Gene name: visual system homeobox 2
Probe: Chx10 cDNA7
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen E14.5 heterozygote: embryonic day 14.5; Vsx2or-J/Vsx2+ (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Present Regionally restricted 3A E14.5 orJ/+ Expression is present in progenitor cells in the outer neuroblastic layer and the periphery of the retina (zone 1 but not zone 2).

Specimen E14.5 homozygote: embryonic day 14.5; Vsx2or-J/Vsx2or-J (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Present 3A E14.5 orJ/orJ Expression is present in the outer neuroblastic layer.

Specimen E17.5 heterozygote: embryonic day 17.5; Vsx2or-J/Vsx2+ (more )
Structure Level Pattern Image Note
TS25: retina outer nuclear layer Present 3A E17.5 orJ/+ Expression is present in progenitor cells in the outer neuroblastic layer.
TS25: neural retina Present Regionally restricted 3A E17.5 orJ/+ Expression is present in the periphery of the retina (zone 1 but not zone 2).

Specimen E17.5 homozygote: embryonic day 17.5; Vsx2or-J/Vsx2or-J (more )
Structure Level Pattern Image Note
TS25: retina outer nuclear layer Present 3A E17.5 orJ/orJ
TS25: retina Present Regionally restricted 3A E17.5 orJ/orJ Expression is present in the center of the eye but is not detected more peripherally in the transdifferentiating region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory