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Gene Expression Data
Assay Details
Assay
Reference: J:94457 Haubst N, et al., Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development. Development. 2004 Dec;131(24):6131-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3524976
Gene symbol: Neurog2
Gene name: neurogenin 2
Antibody: Ngn2 antibody
Detection system: Secondary antibody
Results
Specimen 3A: embryonic day 14.0 (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (Mash1; assay MGI:3524979).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 3A Expression is in neuronal precursors.
TS22: ganglionic eminence Absent 3A There is no expression in precursors of the ganglionic eminence.
Specimen 3A': embryonic day 14.0; Pax6Mhdaaey18/Pax6Mhdaaey18 (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (Mash1; assay MGI:3524979).
Structure Level Pattern Image Note
TS22: cerebral cortex Absent 3A'
Specimen 3B: embryonic day 14.0 (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (Mash1; assay MGI:3524979).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 3B Expression is in neuronal precursors.
TS22: ganglionic eminence Absent 3B There is no expression in precursors of the ganglionic eminence.
Specimen 3B': embryonic day 14.0; Pax6tm1Gfs/Pax6tm1Gfs (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (Mash1; assay MGI:3524979).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 3B' Expression is in neuronal precursors. Expression in this mutant is the same as in wild-type embryos.
TS22: ganglionic eminence Absent 3B' There is no expression in precursors of the ganglionic eminence. Expression in this mutant is the same as in wild-type embryos.
Specimen 3C: embryonic day 14.0 (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (Mash1; assay MGI:3524979).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 3C Expression is in neuronal precursors.
TS22: ganglionic eminence Absent 3C There is no expression in precursors of the ganglionic eminence.
Specimen 3C': embryonic day 14.0; Pax64Neu/Pax64Neu (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (Mash1; assay MGI:3524979).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 3C' Expression is in neuronal precursors. Expression in this mutant is the same as in wild-type embryos.
TS22: ganglionic eminence Absent 3C' There is no expression in precursors of the ganglionic eminence. Expression in this mutant is the same as in wild-type embryos.
Specimen 3D: embryonic day 14.0 (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (Mash1; assay MGI:3524979).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 3D Expression is in neuronal precursors.
TS22: ganglionic eminence Absent 3D There is no expression in precursors of the ganglionic eminence.
Specimen 3D': embryonic day 14.0; Pax6Sey/Pax6Sey (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (Mash1; assay MGI:3524979).
Structure Level Pattern Image Note
TS22: cerebral cortex Absent 3D'
Specimen S2 A: embryonic day 14.0 (more )
Note: Double labeled: red - Neurog2; green - Pax6 (assay MGI:3524993).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted S2A Expression is in neuronal precursors.
Specimen S2 B: embryonic day 14.0; Pax6Mhdaaey18/Pax6Mhdaaey18 (more )
Note: Double labeled: red - Neurog2; green - Pax6 (assay MGI:3524993).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted S2B In this mutant, the number of expressing cells is severely reduced.
Specimen S2 C: embryonic day 14.0; Pax6tm1Gfs/Pax6tm1Gfs (more )
Note: Double labeled: red - Neurog2; green - Pax6 (assay MGI:3524993).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted S2C Expression in this mutant is the same as in wild-type embryos.
Specimen S2 D: embryonic day 14.0; Pax64Neu/Pax64Neu (more )
Note: Double labeled: red - Neurog2; green - Pax6 (assay MGI:3524993).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted S2D Expression in this mutant is the same as in wild-type embryos.
Specimen S2 E: embryonic day 14.0; Pax6Sey/Pax6Sey (more )
Note: Double labeled: red - Neurog2; green - Pax6 (assay MGI:3524993).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted S2E In this mutant, the number of expressing cells is severely reduced.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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