Tgfb2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:92176 Ficker M, et al., Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule. Dev Biol. 2004 Apr 1;268(1):7-23
Assay type:	RNA in situ
MGI Accession ID:	MGI:3511147
Gene symbol:	Tgfb2
Gene name:	transforming growth factor, beta 2

Probe:	Tgfb2 probe4
Probe preparation:	Antisense labelled with S35 RNA
Visualized with:	Autoradiography

Results

4J ©

Specimen 4J: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: otic capsule	Present	Regionally restricted	4J	Expression is in the outermost extent of the capsule.
TS21: inner ear mesenchyme	Absent		4J	Expression is absent from the mesenchyme directly surrounding the vestibular and cochlear epithelia.
TS21: saccule	Strong	Regionally restricted	4J	Expression is in the maculae.
TS21: utricle	Strong	Regionally restricted	4J	Expression is in the maculae.
TS21: lateral semicircular canal	Strong	Regionally restricted	4J	Expression is in the cristae in the base of the canals.
TS21: posterior semicircular canal	Strong	Regionally restricted	4J	Expression is in the cristae in the base of the canals.
TS21: superior semicircular canal	Strong	Regionally restricted	4J	Expression is in the cristae in the base of the canals.
TS21: cochlear duct epithelium	Strong	Regionally restricted	4J	Expression is in the ventral wall.

4K ©

Specimen 4K: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: otic capsule	Present	Regionally restricted	4K	Expression is in the outermost extent of the capsule.
TS21: inner ear mesenchyme	Absent		4K	Expression is absent from the mesenchyme directly surrounding the vestibular and cochlear epithelia.
TS21: inner ear epithelium	Present		4K
TS21: saccule	Strong	Regionally restricted	4K	Expression is in the maculae.
TS21: utricle	Strong	Regionally restricted	4K	Expression is in the maculae.
TS21: lateral semicircular canal	Strong	Regionally restricted	4K	Expression is in the cristae in the base of the canals.
TS21: posterior semicircular canal	Strong	Regionally restricted	4K	Expression is in the cristae in the base of the canals.
TS21: superior semicircular canal	Strong	Regionally restricted	4K	Expression is in the cristae in the base of the canals.
TS21: cochlear duct epithelium	Strong	Regionally restricted	4K	Expresssion is in the ventral wall.

6C ©

Specimen 6C: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: lateral semicircular canal	Present	Regionally restricted	6C	Expression is in the cristae in the base of the canals.
TS23: posterior semicircular canal	Present	Regionally restricted	6C	Expression is in the cristae in the base of the canals.
TS23: superior semicircular canal	Present	Regionally restricted	6C	Expression is in the cristae in the base of the canals.

6D ©

Specimen 6D: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: cochlear duct epithelium	Present		6D

6E ©

Specimen 6E: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: lateral semicircular canal	Present	Regionally restricted	6E	Expression is in patches of sensory/supporting cells of the cristae.
TS25: posterior semicircular canal	Present	Regionally restricted	6E	Expression is in patches of sensory/supporting cells of the cristae.
TS25: superior semicircular canal	Present	Regionally restricted	6E	Expression is in patches of sensory/supporting cells of the cristae.
TS25: saccule	Present	Regionally restricted	6E	Expression is in patches of sensory/supporting cells of the maculae.
TS25: utricle	Present	Regionally restricted	6E	Expression is in patches of sensory/supporting cells of the maculae.
TS25: otic cartilage	Present		6E

6F ©

Specimen 6F: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: cochlear duct epithelium	Present		6F
TS25: otic cartilage	Present		6F

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23