Gene Expression Data
Assay Details
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Assay
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Reference:
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J:57680
Loughna S, et al., A molecular and genetic analysis of renalglomerular capillary development. Angiogenesis. 1997;1(1):84-101
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:3056516
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Gene symbol:
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Tie1
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Gene name:
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tyrosine kinase with immunoglobulin-like and EGF-like domains 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
4A:
embryonic day 10.5; Tie1tm1Jpa/Tie1 +
(more  )
Specimen
4A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tie1tm1Jpa/Tie1+
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Age:
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embryonic day 10.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: genitourinary system |
Present |
Regionally restricted |
4A
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Expression is in the renal and loose mesenchyme and is absent in the Wolffian duct.
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Specimen
4B:
embryonic day 10.5; Tie1tm1Jpa/Tie1 +
(more )
Note: This specimen was gently squashed under a coverslip.
Specimen
4B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tie1tm1Jpa/Tie1+
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Age:
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embryonic day 10.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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This specimen was gently squashed under a coverslip.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: genitourinary system |
Present |
Regionally restricted |
4B
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Expression is in the renal and loose mesenchyme and is absent in the Wolffian duct.
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Specimen
4C,D,E:
embryonic day 11.5; Tie1tm1Jpa/Tie1 +
(more )
Specimen
4C,D,E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tie1tm1Jpa/Tie1+
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Age:
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embryonic day 11.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: metanephros |
Present |
Regionally restricted |
4C
,
4D
,
4E
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Expression is in small cell clusters near the hilum and cortex.
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Specimen
4F,G,H:
embryonic day 12.5; Tie1tm1Jpa/Tie1 +
(more )
Specimen
4F,G,H:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tie1tm1Jpa/Tie1+
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: metanephros |
Present |
Regionally restricted |
4H
,
4F
,
4G
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Expression is radiating from the hilum, corresponding to the capillary network around the main stem of the ureteric bud and in isolated cells in the cortex.
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Specimen
4I:
embryonic day 14.5; Tie1tm1Jpa/Tie1 +
(more )
Specimen
4I:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tie1tm1Jpa/Tie1+
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: renal artery |
Present |
Regionally restricted |
4I
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Expression is in the endothelia.
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| TS22: renal cortex |
Present |
Regionally restricted |
4I
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Expression is in S-shaped bodies.
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Specimen
4J:
embryonic day 15.5; Tie1tm1Jpa/Tie1 +
(more )
Specimen
4J:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tie1tm1Jpa/Tie1+
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Age:
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embryonic day 15.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: maturing glomerular tuft |
Present |
Regionally restricted |
4J
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Expression is in the capillary loops and arteriole of the glomerulus.
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Specimen
Not Shown:
postnatal adult; Tie1tm1Jpa/Tie1 +
(more )
Specimen
Not Shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tie1tm1Jpa/Tie1+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: arterial system |
Present |
Regionally restricted |
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Expression is in the endothelia.
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| TS28: metanephros |
Present |
Regionally restricted |
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Expression is in the endothelia.
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Analysis Tools
