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Gene Expression Data
Assay Details
Assay
Reference: J:91025 Parlakian A, et al., Targeted inactivation of serum response factor in the developing heart results in myocardial defects and embryonic lethality. Mol Cell Biol. 2004 Jun;24(12):5281-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3054947
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen Not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present Single cells Staining is seen in only a few cells.
Specimen Not shown: embryonic day 10.5; Srftm1Zli/Srftm1Zli, Tg(Myh7-cre)1Zli/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: heart Present Single cells As in wild type, staining is seen in only a few cells.
Specimen 5C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: heart Present Single cells 5C There are a few apoptotic cells.
Specimen 5D: embryonic day 11.5; Srftm1Zli/Srftm1Zli, Tg(Myh7-cre)1Zli/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: heart Present Single cells 5D There is a dramatic increase in apoptosis in the mutant.
Specimen Not shown: embryonic day 11.5; Srftm1Zli/Srftm1Zli, Tg(Myh7-cre)1Zli/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: blood vessel Present Single cells Levels of apoptosis in the mutant are greater than those seen in wild type.
TS19: epithelium Present Single cells Levels of apoptosis in the mutant are greater than those seen in wild type.
TS19: limb Present Single cells Levels of apoptosis in the mutant are greater than those seen in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory