Gene Expression Data
Assay Details
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Assay
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Reference:
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J:91057
Louvi A, et al., Presenilin 1 in migration and morphogenesis in the central nervous system. Development. 2004 Jul;131(13):3093-105
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3052224
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Gene symbol:
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Pax6
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Gene name:
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paired box 6
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Results
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Specimen
1K:
embryonic day 11.5
(more  )
Note: flat-mount preparation of the ventral hindbrain
Specimen
1K:
(close  )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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flat-mount preparation of the ventral hindbrain
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: myelencephalon |
Present |
Regionally restricted |
1K
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Expression is in neuronal progenitors.
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Specimen
1L:
embryonic day 11.5; Psen1tm1Pcw/ Psen1tm1Pcw
(more )
Note: flat-mount preparation of the ventral hindbrain
Specimen
1L:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Psen1tm1Pcw/Psen1tm1Pcw
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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flat-mount preparation of the ventral hindbrain
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: myelencephalon |
Present |
Regionally restricted |
1L
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Expression in this mutant is downregulated. There are abnormal streams of expressing cells in ventral r3 and in r5/6.
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Specimen
3I:
embryonic day 16.5
(more )
Specimen
3I:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
3J:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Psen1tm1Pcw/Psen1tm1Pcw
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
7E:
embryonic day 17.5
(more )
Note: coronal section through the caudal midbrain and cerebellum
Specimen
7E:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 17.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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coronal section through the caudal midbrain and cerebellum
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: cerebellum |
Present |
Regionally restricted |
7E
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Expression is in granule cell precursors.
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Specimen
7F:
embryonic day 17.5; Psen1tm1Pcw/ Psen1tm1Pcw
(more )
Note: coronal section through the caudal midbrain and cerebellum
Specimen
7F:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Psen1tm1Pcw/Psen1tm1Pcw
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Age:
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embryonic day 17.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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coronal section through the caudal midbrain and cerebellum
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: cerebellum |
Present |
Regionally restricted |
7F
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Expression in granule cell precursors indicate that cerebellar morphology is affected in this mutant.
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Specimen
7G:
embryonic day 17.5
(more )
Note: coronal section through the caudal midbrain and cerebellum
Specimen
7G:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 17.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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coronal section through the caudal midbrain and cerebellum
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: cerebellum |
Present |
Regionally restricted |
7G
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Expression is in granule cell precursors.
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Specimen
7H:
embryonic day 17.5; Psen1tm1Pcw/ Psen1tm1Pcw
(more )
Note: coronal section through the caudal midbrain and cerebellum
Specimen
7H:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Psen1tm1Pcw/Psen1tm1Pcw
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Age:
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embryonic day 17.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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coronal section through the caudal midbrain and cerebellum
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: cerebellum |
Present |
Regionally restricted |
7H
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Expression is in granule cell precursors. Staining indicates the cerebellum has failed to fuse and the cells are clustered.
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Specimen
7K:
embryonic day 16.5
(more )
Note: sagittal section through caudal midbrain and cerebellum
Specimen
7K:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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sagittal section through caudal midbrain and cerebellum
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: hindbrain |
Present |
Regionally restricted |
7K
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Expression is in the pontine migratory stream of the pontine nucleus.
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Specimen
7L:
embryonic day 16.5; Psen1tm1Pcw/ Psen1tm1Pcw
(more )
Note: sagittal section through caudal midbrain and cerebellum
Specimen
7L:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Psen1tm1Pcw/Psen1tm1Pcw
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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sagittal section through caudal midbrain and cerebellum
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: hindbrain |
Present |
Regionally restricted |
7L
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The migratory stream of granule precursor cells is underpopulated. Expressing cells accumulate ectopically.
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Analysis Tools