About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:89167 Schumacher N, et al., Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain. Gene Expr Patterns. 2004 May;4(3):249-55
Assay type: RNA in situ
MGI Accession ID: MGI:3044973
Gene symbol: Spire1
Gene name: spire type actin nucleation factor 1
Probe: pcDNA3-Myc-m-Spir-1-CT
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3, cross section: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord ventricular layer Strong 3_spir-1 cross section
TS22: spinal cord Present Graded 3_spir-1 cross section Expression is strongest in the ventricular zone and is weak outside this region.
TS22: dorsal root ganglion Weak 3_spir-1 cross section
Specimen 3, sagittal: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Present Uniform 3_spir-1 sagittal section
TS22: spinal cord Present Uniform 3_spir-1 sagittal section
TS22: trigeminal ganglion Present Uniform 3_spir-1 sagittal section
TS22: liver Present Spotted 3_spir-1 sagittal section
Specimen 3, telencephalon: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon Present 3_spir-1 telencephalon
TS22: trigeminal ganglion Present 3_spir-1 telencephalon
Specimen 3, mesencephalon: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midbrain Present 3_spir-1 mesencephalon
Specimen 4A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present 4A spir-1 hippocampus
TS28: hippocampus CA2 Present 4A spir-1 hippocampus
TS28: hippocampus CA3 Present 4A spir-1 hippocampus
TS28: dentate gyrus granule cell layer Strong 4A spir-1 hippocampus
TS28: hippocampus Present Regionally restricted 4A spir-1 hippocampus Expression is present in neuronal layers.
TS28: corpus callosum Absent 4A spir-1 hippocampus Absent in the white matter.
Specimen 4B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 4B spir-1 cerebellum
TS28: cerebellum granule cell layer Present Spotted 4B spir-1 cerebellum
TS28: cerebellum molecular layer Weak 4B spir-1 cerebellum
TS28: corpus callosum Absent 4B spir-1 cerebellum
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory