Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:89188
Raft S, et al., Suppression of neural fate and control of inner ear morphogenesis by Tbx1. Development. 2004 Apr;131(8):1801-12
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:3044708
|
Gene symbol:
|
Neurod1
|
Gene name:
|
neurogenic differentiation 1
|
Probe:
|
neuroD probe1
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
Visualized with:
|
Alkaline phosphatase
|
|
Results
|
Specimen
1D:
embryonic day 9.0
(more )
Note: 15-16 somite stage.
Specimen
1D:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 9.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
15-16 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: otic placode epithelium |
Present |
Regionally restricted |
1D
|
Expression is located near the AP midline of the placode and coincides with that of Neurog1. Expression occurs near a border of Tbx1 expression.
|
Specimen
1E:
embryonic day 9.0
(more )
Note: 18-19 somite stage.
Specimen
1E:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 9.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
18-19 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: otic placode epithelium |
Present |
Regionally restricted |
1E
|
The expression domain coincides with Neurog1 and extends into the anterolateral, anteroventral and posteroventral portions of the invaginating placode. Expression overlaps with the low-level Tbx1 signal posteriorly.
|
Specimen
2D:
embryonic day 9.5
(more )
Note: 22-24 somite stage.
Specimen
2D:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
22-24 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: otocyst epithelium |
Present |
Regionally restricted |
2D
|
A border of expression is seen at the AP midline and the posterolateral region shows no expression.
|
Specimen
2E:
embryonic day 10.0
(more )
Note: 29-31 somite stage.
Specimen
2E:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
29-31 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
2E
|
A border of expression is seen at the AP midline and the posterolateral region shows no expression. The expression is complementary to that of Tbx1.
|
Specimen
2F:
embryonic day 11.0
(more )
Note: 40-42 somite stage.
Specimen
2F:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
40-42 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: otocyst epithelium |
Present |
Regionally restricted |
2F
|
A border of expression is seen at the AP midline and the posterolateral region shows no expression. The expression is complementary to that of Tbx1.
|
Specimen
2G:
embryonic day 9.5; Tbx1tm1Bem/Tbx1 +
(more )
Note: 22-24 somite stage.
Specimen
2G:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1+
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
22-24 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: otocyst epithelium |
Present |
Regionally restricted |
2G
|
There is ectopic expression posteroventromedially.
|
Specimen
2H:
embryonic day 10.0; Tbx1tm1Bem/Tbx1 +
(more )
Note: 29-31 somite stage.
Specimen
2H:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1+
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
29-31 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
2H
|
There is extopic expression posteroventromedially and anterodorsolaterally.
|
Specimen
2I:
embryonic day 11.0; Tbx1tm1Bem/Tbx1 +
(more )
Note: 40-42 somite stage.
Specimen
2I:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1+
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
40-42 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: otocyst epithelium |
Present |
Regionally restricted |
2I
|
There is extopic expression posteroventromedially and anterodorsolaterally.
|
Specimen
2J:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
22-24 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: otic placode epithelium |
Present |
Regionally restricted |
2J
|
There is a uniform distribution of expression along the A-P axis and no AP midline border forms.
|
Specimen
2K:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
29-31 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
2K
|
There is a uniform distribution of expression along the A-P axis and no AP midline border forms.
|
Specimen
2L:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
40-42 somite stage.
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: otocyst epithelium |
Present |
Regionally restricted |
2L
|
There is a uniform distribution of expression along the A-P axis and no AP midline border forms.
|
Specimen
3I:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: otocyst epithelium |
Present |
Regionally restricted |
3I
|
There is a uniform distribution of expression along the A-P axis and no AP midline border forms.
|
Specimen
3J:
embryonic day 10.5
(more )
Specimen
3J:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: otocyst epithelium |
Present |
Regionally restricted |
3J
|
A border of expression is seen at the AP midline and the posterolateral region shows no expression. The expression is complementary to that of Tbx1.
|
Specimen
S1F:
embryonic day 10.0
(more )
Note: The series F-J represents sections from anterior to posterior.
Specimen
S1F:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series F-J represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1F
|
There is no overlap between this expression and that of Tbx1 shown in Fig. S1A-S1E.
|
Specimen
S1G:
embryonic day 10.0
(more )
Note: The series F-J represents sections from anterior to posterior.
Specimen
S1G:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series F-J represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1G
|
There is no overlap between this expression and that of Tbx1 shown in Fig. S1A-S1E.
|
Specimen
S1H:
embryonic day 10.0
(more )
Note: The series F-J represents sections from anterior to posterior.
Specimen
S1H:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series F-J represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1H
|
There is no overlap between this expression and that of Tbx1 shown in Fig. S1A-S1E.
|
Specimen
S1I:
embryonic day 10.0
(more )
Note: The series F-J represents sections from anterior to posterior.
Specimen
S1I:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series F-J represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1I
|
There is no overlap between this expression and that of Tbx1 shown in Fig. S1A-S1E.
|
Specimen
S1J:
embryonic day 10.0
(more )
Note: The series F-J represents sections from anterior to posterior.
Specimen
S1J:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series F-J represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1J
|
There is no overlap between this expression and that of Tbx1 shown in Fig. S1A-S1E.
|
Specimen
S1K:
embryonic day 10.0; Tbx1tm1Bem/Tbx1 +
(more )
Note: The series K-O represents sections from anterior to posterior.
Specimen
S1K:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1+
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series K-O represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1K
|
There is an incresed accumulation of delaminated, expressing cells.
|
Specimen
S1L:
embryonic day 10.0; Tbx1tm1Bem/Tbx1 +
(more )
Note: The series K-O represents sections from anterior to posterior.
Specimen
S1L:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1+
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series K-O represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1L
|
There is an incresed accumulation of delaminated, expressing cells.
|
Specimen
S1M:
embryonic day 10.0; Tbx1tm1Bem/Tbx1 +
(more )
Note: The series K-O represents sections from anterior to posterior.
Specimen
S1M:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1+
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series K-O represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1M
|
There is an incresed accumulation of delaminated, expressing cells.
|
Specimen
S1N:
embryonic day 10.0; Tbx1tm1Bem/Tbx1 +
(more )
Note: The series K-O represents sections from anterior to posterior.
Specimen
S1N:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1+
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series K-O represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1N
|
There is an incresed accumulation of delaminated, expressing cells.
|
Specimen
S1O:
embryonic day 10.0; Tbx1tm1Bem/Tbx1 +
(more )
Note: The series K-O represents sections from anterior to posterior.
Specimen
S1O:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1+
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series K-O represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1O
|
There is an incresed accumulation of delaminated, expressing cells.
|
Specimen
S1P:
embryonic day 10.0; Tbx1tm1Bem/ Tbx1tm1Bem
(more )
Note: The series P-T represents sections from anterior to posterior.
Specimen
S1P:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series P-T represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1P
|
The extreme dorsal and medial borders of expression seen in wild-type embryos and the signal gradient along the medial-lateral axis are mainatained in these mutants.
|
Specimen
S1Q:
embryonic day 10.0; Tbx1tm1Bem/ Tbx1tm1Bem
(more )
Note: The series P-T represents sections from anterior to posterior.
Specimen
S1Q:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series P-T represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1Q
|
The extreme dorsal and medial borders of expression seen in wild-type embryos and the signal gradient along the medial-lateral axis are mainatained in these mutants.
|
Specimen
S1R:
embryonic day 10.0; Tbx1tm1Bem/ Tbx1tm1Bem
(more )
Note: The series P-T represents sections from anterior to posterior.
Specimen
S1R:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series P-T represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1R
|
The extreme dorsal and medial borders of expression seen in wild-type embryos and the signal gradient along the medial-lateral axis are mainatained in these mutants.
|
Specimen
S1S:
embryonic day 10.0; Tbx1tm1Bem/ Tbx1tm1Bem
(more )
Note: The series P-T represents sections from anterior to posterior.
Specimen
S1S:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series P-T represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1S
|
The extreme dorsal and medial borders of expression seen in wild-type embryos and the signal gradient along the medial-lateral axis are mainatained in these mutants.
|
Specimen
S1T:
embryonic day 10.0; Tbx1tm1Bem/ Tbx1tm1Bem
(more )
Note: The series P-T represents sections from anterior to posterior.
Specimen
S1T:
(close )
Genetic Background:
|
involves: 129/Sv * C57BL/6J * FVB * SJL
|
Mutant Allele(s):
|
Tbx1tm1Bem/Tbx1tm1Bem
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
The series P-T represents sections from anterior to posterior.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: otocyst epithelium |
Present |
Regionally restricted |
S1T
|
The extreme dorsal and medial borders of expression seen in wild-type embryos and the signal gradient along the medial-lateral axis are mainatained in these mutants.
|
|