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Gene Expression Data
Assay Details
Assay
Reference: J:58382 Dho SE, et al., Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain. J Biol Chem. 1999 Nov 12;274(46):33097-104
Assay type: Western blot
MGI Accession ID: MGI:3040065
Gene symbol: Numb
Gene name: NUMB endocytic adaptor protein
Antibody: anti-NB-C
Assay notes: Samples were immunoprecipitated using the anti-Nb-C antibody (MGI:3040050) prior to immunoblotting.
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure 72 kDa (a) 71 kDa (b) 66 kDa (c) 65 kDa (d) Size Not Specified (e) Genetic BackgroundMutant Allele(s)Sex
brain P adult TS28: brain Not Specified Present Present Present Not Specified Not Specified Not Specified
lung P adult TS28: lung Not Specified Present Present Present Not Specified Not Specified Not Specified
testis P adult TS28: testis Not Specified Present Absent Present Not Specified Not Specified Male
thymus P adult TS28: thymus Not Specified Present Present Present Not Specified Not Specified Not Specified
embryo d12 E12.0 (f) TS20: embryo Not Specified Present Present Present Not Specified Not Specified Not Specified
Notes:
(a) Corresponding to isoform containing both inserts. Authors state that unequivocal identification of the 72-kDa isoform could not be made.
(b) Corresponding to isoform containing only the 49 amino acid PRR insert.
(c) Corresponding to isoform containing only the 11 amino acid PTB insert.
(d) Corresponding to isoform without either insert.
(e) Corresponding to the Numbl gene product, also recognized by the anti-Nb-C antibody.
(f) Age of embryo at noon of plug day not specified in reference.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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