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Gene Expression Data
Assay Details
Assay
Reference: J:61350 Mucchielli ML, et al., Correlation of asymmetric Notch2 expression and mouse incisor rotation. Mech Dev. 2000 Mar 1;91(1-2):379-82
Assay type: RNA in situ
MGI Accession ID: MGI:3029810
Gene symbol: Notch2
Gene name: notch 2
Probe: Notch2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2B: embryonic day 11.0 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component ectoderm Present Regionally restricted 2B Expression is in the anterior part of the invaginating epithelial cells of the developing incisor. Expression is absent in the epithelial cells contacting the mesenchyme.
Specimen 2D: embryonic day 11.0 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component ectoderm Present Regionally restricted 2D Expression is in the anterior part of the invaginating epithelial cells of the developing incisor. Expression is absent in the epithelial cells contacting the mesenchyme.
Specimen 3B: embryonic day 13.5 (more )
Note: Bud and cap stage of incisor development.
Structure Level Pattern Image Note
TS21: lower jaw incisor epithelium Present Regionally restricted 3B Expression is in the labial part of the incisor epithelium.
TS21: lower jaw incisor Present Regionally restricted 3B Expression is in the incisor furrow.
TS21: lower jaw incisor mesenchyme Weak 3B
Specimen 3C: embryonic day 13.5 (more )
Note: Bud and cap stage of incisor development.
Structure Level Pattern Image Note
TS21: upper jaw incisor epithelium Present Regionally restricted 3C Expression is in the anterior part of the incisor epithelium.
Specimen 3E: embryonic day 13.5 (more )
Note: Bud and cap stage of incisor development.
Structure Level Pattern Image Note
TS21: lower jaw incisor epithelium Present Regionally restricted 3E Expression is in the labial part of the incisor epithelium.
TS21: lower jaw incisor Present Regionally restricted 3E Expression is in the incisor furrow.
TS21: lower jaw incisor mesenchyme Weak 3E
Specimen 4B: embryonic day 11.0 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component ectoderm Present Regionally restricted 4B Expression is in the middle of the molar dental epithelium.
Specimen 4D: embryonic day 14.0 (more )
Note: Cap stage of incisor development.
Structure Level Pattern Image Note
TS22: cap stage tooth Present 4D
TS22: stratum intermedium Present 4D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory