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Gene Expression Data
Assay Details
Assay
Reference: J:41123 Wyatt S, et al., Sympathetic neuron survival and TrkA expression in NT3-deficient mouse embryos. EMBO J. 1997 Jun 2;16(11):3115-23
Assay type: RT-PCR
MGI Accession ID: MGI:2686675
Gene symbol: Ntrk3
Gene name: neurotrophic tyrosine kinase, receptor, type 3
Probe: trkC-pA, trkC-pB
Assay notes: Shown are levels of transcripts relative to GAPDH. Primer set amplifies all trkC transcripts. Levels of transcripts lacking the tyrosine kinase domain (TK-) were calculated by subtracting TK+ levels (assayed using primers trkC-pA and trkC-pB; see assayMGI:2686673) from total trkC levels.
Results Image: 6_trkC TK-
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (b) Amount Genetic BackgroundMutant Allele(s)Sex
E14 NT3+/+ E14.0 (a) TS22: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
E15 NT3+/+ E15.0 (a) TS23: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
E16 NT3+/+ E16.0 (a) TS24: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
E18 NT3+/+ E18.0 (a) TS26: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
P1 NT3+/+ P1 TS27: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
E14 NT3-/- E14.0 (a) TS22: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E15 NT3-/- E15.0 (a) TS23: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E16 NT3-/- E16.0 (a) TS24: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E18 NT3-/- E18.0 (a) TS26: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
P1 NT3-/- P1 TS27: superior cervical ganglion Present 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference. Authors state the precise stage of development was determined by the criteria of Theiler (1972).
(b) Authors state that levels were very similar in both genotypes, with levels of TK- transcripts substantially higher than TK+.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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