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Gene Expression Data
Assay Details
Assay
Reference: J:41123 Wyatt S, et al., Sympathetic neuron survival and TrkA expression in NT3-deficient mouse embryos. EMBO J. 1997 Jun 2;16(11):3115-23
Assay type: RT-PCR
MGI Accession ID: MGI:2686670
Gene symbol: Ngfr
Gene name: nerve growth factor receptor (TNFR superfamily, member 16)
Probe: p75-pA, p75-pB
Assay notes: Shown are absolute levels per ganglion and levels relative to the level of L27 mRNA.
Results Image: 3_p75
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
E14 NT3+/+ E14.0 (a) TS22: superior cervical ganglion Absent (b) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
E14.5 NT3+/+ E14.5 (a) TS22: superior cervical ganglion Trace (b) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
E15 NT3+/+ E15.0 (a) TS22: superior cervical ganglion Present (b) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
E16 NT3+/+ E16.0 (a) TS24: superior cervical ganglion Present (b) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
E18 NT3+/+ E18.0 (a) TS26: superior cervical ganglion Present (b) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified
P1 NT3+/+ P1 TS27: superior cervical ganglion Present (b) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Not Specified Stellate ganglion and ganglia of the branchial part of the sympathetic chain.
E14 NT3-/- E14.0 (a) TS22: superior cervical ganglion Absent (c) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E14.5 NT3-/- E14.5 (a) TS22: superior cervical ganglion Trace (c) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E15.0 NT3-/- E15.0 (a) TS23: superior cervical ganglion Present (c) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E16.0 NT3-/- E16.0 (a) TS24: superior cervical ganglion Present (d) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E18.0 NT3-/- E18.0 (a) TS26: superior cervical ganglion Present (e) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
P1 NT3-/- P1 TS27: superior cervical ganglion Present (e) 1 µg; poly-A+ RNA involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference. Authors state the precise stage of development was determined by the criteria of Theiler (1972).
(b) Absolute levels increased from E14 to P1.
(c) Levels increased up to E16.
(d) Not significantly different from wild-type.
(e) Absolute level and level relative to L27 were both significantly lower than wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory