About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:87042 Krebs O, et al., Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud. Development. 2003 Dec;130(24):6037-47
Assay type: Western blot
MGI Accession ID: MGI:2684134
Gene symbol: Shh
Gene name: sonic hedgehog
Results
Image: 6C ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
wt/wt FL E11.5 (a) TS19: forelimb bud Present involves: C3H/HeJ Not Specified
wt/wt HL E11.5 (a) TS19: hindlimb bud Present involves: C3H/HeJ Not Specified
wt/raz FL E11.5 (a) TS19: forelimb bud Present (b) C3.D2-Raz Raz/Raz+Not Specified
wt/raz E11.5 (a) TS19: hindlimb bud Present (b) C3.D2-Raz Raz/Raz+Not Specified
raz/raz FL E11.5 (a) TS19: forelimb bud Weak (c) C3.D2-Raz Raz/RazNot Specified
raz/raz HL E11.5 (a) TS19: hindlimb bud Weak (c) C3.D2-Raz Raz/RazNot Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Level of expression was about 60% of wild-type.
(c) Author report low levels of expression; ~20% that of wild-type.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/28/2026
MGI 6.24
The Jackson Laboratory