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Gene Expression Data
Assay Details
Assay
Reference: J:84651 Yamazaki D, et al., WAVE2 is required for directed cell migration and cardiovascular development. Nature. 2003 Jul 24;424(6947):452-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2678524
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Results
Specimen 1g,h: embryonic day 9.5 (more )
Note: 27 somites. Panel h shows a merged image with the results of two antibodies. This is a transverse section at the level of the dorsal aorta.
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 1g , 1h Expression is in endothelial cells.
TS15: dorsal aorta Present Regionally restricted 1g , 1h Expression is in endothelial cells.
Specimen 1j,k: embryonic day 9.5 (more )
Note: 27 somites. Panel k shows a merged image with the results of two antibodies. This is a transverse section at the level of the heart.
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 1k , 1j Expression is in endothelial cells.
TS15: heart Present Regionally restricted 1k , 1j Expression is in endothelial cells.
Specimen 1m,n: embryonic day 9.5 (more )
Note: 27 somites. Panel n shows a merged image with the results of two antibodies. This is a transverse section at the level of the dorsal aorta.
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 1n , 1m Expression is in endothelial cells.
TS15: dorsal aorta Present Regionally restricted 1n , 1m Expression is in endothelial cells.
Specimen 2a: embryonic day 9.0 (more )
Note: 18 somites. This field is the head region.
Structure Level Pattern Image Note
TS14: blood vessel Present Regionally restricted 2a Expression is in endothelial cells.
TS14: head Present Regionally restricted 2a Expression is in endothelial cells.
Specimen 2b: embryonic day 9.0; Wasf2tm1Tta/Wasf2tm1Tta (more )
Note: 18 somites. This field is the head region.
Structure Level Pattern Image Note
TS14: blood vessel Present Regionally restricted 2b Expression is in endothelial cells. Expression in this mutant is the same as in wild-type embryos.
TS14: head Present Regionally restricted 2b Expression is in endothelial cells. Expression in this mutant is the same as in wild-type embryos.
Specimen 2c: embryonic day 9.0 (more )
Note: 18 somites. This field is the trunk region.
Structure Level Pattern Image Note
TS14: blood vessel Present Regionally restricted 2c Expression is in endothelial cells.
Specimen 2d: embryonic day 9.0; Wasf2tm1Tta/Wasf2tm1Tta (more )
Note: 18 somites. This field is the trunk region.
Structure Level Pattern Image Note
TS14: blood vessel Present Regionally restricted 2d Expression is in endothelial cells. The vessels are disorganized in this mutant.
Specimen 2e: embryonic day 9.5 (more )
Note: 22 somites. Yolk sac
Structure Level Pattern Image Note
TS15: extraembryonic arterial system Present Regionally restricted 2e Expression is in endothelial cells.
TS15: extraembryonic venous system Present Regionally restricted 2e Expression is in endothelial cells.
Specimen 2f: embryonic day 9.5; Wasf2tm1Tta/Wasf2tm1Tta (more )
Note: 22 somites. Yolk sac
Structure Level Pattern Image Note
TS15: extraembryonic arterial system Present Regionally restricted 2f Expression is in endothelial cells. Cappilaries are small and sometimes discontinuous.
TS15: extraembryonic venous system Present Regionally restricted 2f Expression is in endothelial cells. Cappilaries are small and sometimes discontinuous.
Specimen 2g: embryonic day 9.5 (more )
Note: 22 somites. This field is the head region.
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 2g Expression is in endothelial cells.
TS15: head Present Regionally restricted 2g Expression is in endothelial cells.
Specimen 2h: embryonic day 9.5; Wasf2tm1Tta/Wasf2tm1Tta (more )
Note: 22 somites. This field is the head region.
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 2h Expression is in endothelial cells. capillaries are less dense and branched than in wild-type embryos.
TS15: head Present Regionally restricted 2h Expression is in endothelial cells. capillaries are less dense and branched than in wild-type embryos.
Specimen 2i,k: embryonic day 9.5 (more )
Note: 22 somites. This field is the trunk region.
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 2k , 2i Expression is in endothelial cells.
Specimen 2j,l: embryonic day 9.5; Wasf2tm1Tta/Wasf2tm1Tta (more )
Note: 22 somites. This field is the trunk region.
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 2l , 2j Expression is in endothelial cells. The major vessels are small when compared to wild-type embryos.
Specimen 2m: embryonic day 9.5 (more )
Note: 27 somites. This field is the trunk region.
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 2m Expression is in endothelial cells.
TS15: head Present Regionally restricted 2m Expression is in endothelial cells.
Specimen 2n: embryonic day 9.5; Wasf2tm1Tta/Wasf2tm1Tta (more )
Note: 27 somites. This field is the trunk region.
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 2n Expression is in endothelial cells.
TS15: head Present Regionally restricted 2n Expression is in endothelial cells.
Specimen S3a: embryonic day 9.0 (more )
Note: 18 somites. This field shows the heart region.
Structure Level Pattern Image Note
TS14: common atrial chamber endocardial tube Present S3a
TS14: primitive ventricle endocardial tube Present S3a
Specimen S3b: embryonic day 9.0; Wasf2tm1Tta/Wasf2tm1Tta (more )
Note: 18 somites. This field shows the heart region.
Structure Level Pattern Image Note
TS14: common atrial chamber endocardial tube Present S3b Expression in this mutant is the same as in wild-type embryos.
TS14: primitive ventricle endocardial tube Present S3b Expression in this mutant is the same as in wild-type embryos.
Specimen S3c: embryonic day 9.5 (more )
Note: 22 somites. This field shows the heart region.
Structure Level Pattern Image Note
TS15: common atrial chamber endocardial lining Present Regionally restricted S3c Expression is in endothelial cells.
TS15: primitive ventricle endocardial lining Present Regionally restricted S3c Expression is in endothelial cells.
Specimen S3d: embryonic day 9.5; Wasf2tm1Tta/Wasf2tm1Tta (more )
Note: 22 somites. This field shows the heart region.
Structure Level Pattern Image Note
TS15: common atrial chamber endocardial lining Present S3d The ventricular endocardium is less complex and the atrial endocardium is collapsed compared to wild-type embryos.
TS15: primitive ventricle endocardial lining Present S3d The ventricular endocardium is less complex and the atrial endocardium is collapsed compared to wild-type embryos.
Specimen S3e: embryonic day 9.5 (more )
Note: 22 somites. This field shows the heart region.
Structure Level Pattern Image Note
TS15: common atrial chamber endocardial lining Present S3e
TS15: primitive ventricle endocardial lining Present S3e
Specimen S3f: embryonic day 9.5; Wasf2tm1Tta/Wasf2tm1Tta (more )
Note: 22 somites. This field shows the heart region.
Structure Level Pattern Image Note
TS15: common atrial chamber endocardial lining Present S3f The endocardium has not expanded, but is properly attached to the myocardium.
TS15: primitive ventricle endocardial lining Present S3f The endocardium has not expanded, but is properly attached to the myocardium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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