Gene Expression Data
Assay Details
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Assay
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Reference:
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J:83256
Naiche LA, et al., Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois. Development. 2003 Jun;130(12):2681-93
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:2677418
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Gene symbol:
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Pecam1
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Gene name:
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platelet/endothelial cell adhesion molecule 1
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Antibody:
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MEC 13.3
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Detection system:
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horseradish peroxidase
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Results
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Specimen
3N, +/+:
embryonic day 7.5
(more  )
Note: 0 somite stage.
Specimen
3N, +/+:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.5
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Age Note:
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Embryonic age was assigned based on somite numbers reported in the paper.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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0 somite stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: extraembryonic component |
Present |
Regionally restricted |
3N +/+
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Expression in differentiating endothelial cells, appearing as clumps in the allantois.
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Specimen
3N, -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tbx4tm1.1Pa/Tbx4tm1.1Pa
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Age:
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embryonic day 7.5
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Age Note:
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Embryonic age was assigned based on somite numbers reported in the paper.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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0 somite stage.
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Specimen
3O, +/+:
embryonic day 8.0
(more )
Note: 4 somite stage.
Specimen
3O, +/+:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.0
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Age Note:
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Embryonic age was assigned based on somite numbers reported in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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4 somite stage.
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Specimen
3O, -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tbx4tm1.1Pa/Tbx4tm1.1Pa
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Age:
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embryonic day 8.0
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Age Note:
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Embryonic age was assigned based on somite numbers reported in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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4 somite stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: extraembryonic component |
Present |
Regionally restricted |
3O -/-
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Numerous clumps of expressing cells along the length of the allantois, but no elongated vessels are seen.
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Specimen
3P, +/+:
embryonic day 8.5
(more )
Note: 8 somite stage.
Specimen
3P, +/+:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Age Note:
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Embryonic age was assigned based on somite numbers reported in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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8 somite stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: extraembryonic vascular system |
Present |
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3P +/+
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Endothelial cells resolve into a central vessel at the base of the allantois, with unincorporated vessels still apparent distally.
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Specimen
3P, -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Tbx4tm1.1Pa/Tbx4tm1.1Pa
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Age:
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embryonic day 8.5
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Age Note:
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Embryonic age was assigned based on somite numbers reported in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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8 somite stage.
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