Gene Expression Data
Assay Details
Assay
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Reference:
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J:42574
Floss T, et al., A role for FGF-6 in skeletal muscle regeneration. Genes Dev. 1997 Aug 15;11(16):2040-51
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2674942
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Gene symbol:
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Myod1
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Gene name:
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myogenic differentiation 1
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Probe:
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MyoD probe12
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
8A:
(close )
Genetic Background:
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either: (involves: 129S4/SvJae-Fgf6tm1Thbr) or (involves: 129S4/SvJae * C57BL/6)
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Mutant Allele(s):
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Fgf6tm1Thbr/Fgf6tm1Thbr
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS28: diaphragm |
Absent |
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8A
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Authors report only background signals.
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Specimen
8B:
(close )
Genetic Background:
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involves: C57BL/10ScSn
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Mutant Allele(s):
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Dmdmdx/Dmdmdx
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS28: diaphragm |
Strong |
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8B
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Authors state that mdx mutants are characerized by an up-regulation of MyoD in skeletal muscles.
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Specimen
8C:
(close )
Genetic Background:
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involves: 129S4/SvJae * C57BL/6 * C57BL/10ScSn
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Mutant Allele(s):
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Dmdmdx/Dmdmdx Fgf6tm1Thbr/Fgf6tm1Thbr
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS28: diaphragm |
Absent |
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8C
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Authors state that lack of Fgf6 leads to reduction of MyoD mRNA in mdx mice.
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