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Gene Expression Data
Assay Details
Assay
Reference: J:82458 Davenport TG, et al., Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome. Development. 2003 May;130(10):2263-73
Assay type: RNA in situ
MGI Accession ID: MGI:2674060
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe23
Assay notes: Some experiments may also have been performed on Swiss-Webster and ICR backgrounds. Authors state that identical phenotypes were seen on all backgrounds, and therefore all data was combined.
Results
Specimen 5A +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present 5A +/+
TS17: hindlimb bud apical ectodermal ridge Present 5A +/+
Specimen 5A -/-: embryonic day 10.5; Tbx3tm1Pa/Tbx3tm1Pa (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present 5A -/- The apical ectodermal ridge was reduced in the forelimb of mutants.
TS17: hindlimb bud apical ectodermal ridge Present 5A -/- The apical ectodermal ridge was more severely reduced in the hindlimb of mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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