About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:81324 Smart N, et al., A differential screen for putative targets of the bHLH transcription factor Hand1 in cardiac morphogenesis. Mech Dev. 2002 Dec;119 Suppl 1:S65-71
Assay type: RNA in situ
MGI Accession ID: MGI:2671311
Gene symbol: Tmsb4x
Gene name: thymosin, beta 4, X chromosome
Probe: Tmsb4x cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: outflow tract Present 2A
TS16: primitive ventricle Present Regionally restricted 2A Expression is at the anterior-frontal region.

Specimen 2B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: outflow tract Present 2B
TS16: primitive ventricle cardiac muscle Present Regionally restricted 2B Expression is at the anterior-frontal region.
TS16: migrating neural crest Present Regionally restricted 2B Expression is in the presumptive cardiac neural crest migrating through the pharyngeal arch region.

Specimen 2C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: outflow tract Present Regionally restricted 2C Expression is in two distinct areas.

Specimen 2D: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: primitive ventricle cardiac muscle Present Regionally restricted 2D Expression is at the anterior-frontal region.
TS16: migrating neural crest Present Regionally restricted 2D Expression is in the presumptive cardiac neural crest migrating through the pharyngeal arch region.
TS16: atrioventricular canal Present 2D
TS16: endocardial cushion Present 2D
TS16: bulbus cordis caudal half endocardial lining Present 2D
TS16: bulbus cordis rostral half endocardial lining Present 2D
TS16: common atrial chamber left part endocardial lining Present 2D
TS16: common atrial chamber right part endocardial lining Present 2D
TS16: left auricular region endocardial lining Present 2D
TS16: outflow tract endocardial tube Present 2D
TS16: primitive ventricle endocardial lining Present 2D
TS16: right auricular region endocardial lining Present 2D
TS16: heart Present Regionally restricted 2D Expression is in the pericardium.

Specimen 2E: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: atrioventricular canal Present 2E
TS16: endocardial cushion Present 2E
TS16: bulbus cordis caudal half endocardial lining Present 2E
TS16: bulbus cordis rostral half endocardial lining Present 2E
TS16: common atrial chamber left part endocardial lining Present 2E
TS16: common atrial chamber right part endocardial lining Present 2E
TS16: left auricular region endocardial lining Present 2E
TS16: outflow tract endocardial tube Present 2E
TS16: primitive ventricle endocardial lining Present 2E
TS16: right auricular region endocardial lining Present 2E

Specimen 5A, +/+: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: primitive heart tube Weak 5A

Specimen 5B, -/-: embryonic day 8.0; Hand1tm1Jcc/Hand1tm1Jcc (more )
Structure Level Pattern Image Note
TS12: heart Absent 5B
TS12: head somite Present 5B
TS12: trunk somite Present 5B
TS12: yolk sac Present Regionally restricted 5B Expression is in the vasculature.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory